Substrate-controlled and highly stereoselective synthesis of 2-aminobut-2-ene-1, 4-diones

被引：14
|
作者：
Deng, Cong [1 ]
Yang, Yan [1 ]
Gao, Meng [1 ]
Zhu, Yan-Ping [1 ]
Wu, An-Xin [1 ]
Ma, Jun-Rui [2 ]
Yin, Guo-Dong [2 ]
机构：
[1] Cent China Normal Univ, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China
[2] Hubei Normal Univ, Hubei Key Lab Pollutant Anal & Reuse Technol, Huangshi 435002, Peoples R China
来源：
TETRAHEDRON | 2012年 / 68卷 / 20期
基金：
中国国家自然科学基金;
关键词：
Aryl methyl ketones; Amines; 2-Aminobut-2-ene-1,4-diones; Substrate-controlled; Z/E-Stereoselectivity; UNSYMMETRICAL BIARYLS; ADDITION-REACTIONS; TRANSFORMATION; DERIVATIVES; STRATEGY; 1,4-DIARYL-2-(ARYLAMINO)BUT-2-ENE-1,4-DIONES; DIBENZOYLACETYLENE; 2H-PYRAN-2-ONES; REARRANGEMENTS; REACTIVITY;
D O I：
10.1016/j.tet.2012.03.049
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
2-Methylthio-substituted 1,4-enediones, obtained from readily available aryl methyl ketones, were reacted with primary or secondary amines to afford the desired 1,4-diaryl-2-aminobut-2-ene-1,4-diones in excellent yields with high Z/E-stereoselectivity. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3828 / 3834
页数：7
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