TARGETING BCMA ACHIEVES DEEP AND DURABLE RESPONSES IN MULTIPLE MYELOMA

被引:0
|
作者
不详
机构
关键词
D O I
10.1158/2159-8290.CD-RW2018-203
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Targeting BCMA with the antibody-drug conjugate GSK2857916 is well tolerated in a phase I trial. ©2019 American Association for Cancer Research.
引用
收藏
页码:12 / 12
页数:1
相关论文
共 50 条
  • [21] Targeting BCMA to Treat Multiple Myeloma: Updates From the 2021 ASH Annual Meeting
    Guo, Ruiting
    Lu, Wenyi
    Zhang, Yi
    Cao, Xinping
    Jin, Xin
    Zhao, Mingfeng
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [22] Serial treatment of relapsed/refractory multiple myeloma with different BCMA-targeting therapies
    Cohen, Adam D.
    Garfall, Alfred L.
    Dogan, Ahmet
    Lacey, Simon F.
    Martin, Chris
    Lendvai, Nikoletta
    Vogl, Dan T.
    Spear, Matthew
    Lesokhin, Alexander M.
    BLOOD ADVANCES, 2019, 3 (16) : 2487 - 2490
  • [23] Elranatamab, a BCMA Targeted T-Cell Engaging Bispecific Antibody, Induces Durable Clinical and Molecular Responses for Patients with Relapsed or Refractory Multiple Myeloma
    Raje, Noopur
    Bahlis, Nizar Jacques
    Costello, Caitlin
    Dholaria, Bhagirathbhai
    Solh, Melhem
    Levy, Moshe Yair
    Tomasson, Michael H.
    Damore, Michael A.
    Jiang, Sibo
    Basu, Cynthia
    Skoura, Athanasia
    Chan, Edward M.
    Trudel, Suzanne
    Jakubowiak, Andrzej
    Chu, Michael P.
    Gasparetto, Cristina J.
    Dalovisio, Andrew P.
    Sebag, Michael
    Lesokhin, Alexander M.
    BLOOD, 2022, 140
  • [24] Clinical responses and pharmacokinetics of fully human BCMA targeting CAR T-cell therapy in relapsed/refractory multiple myeloma.
    Li, Chunrui
    Zhou, Jianfeng
    Wang, Jue
    Hu, Guang
    Du, Aihua
    Zhou, Xiaoxi
    Meng, Li
    Hong, Zhenya
    Chen, Liting
    Mao, Xia
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [25] BCMA-targeted immunotherapy for multiple myeloma
    Yu, Bo
    Jiang, Tianbo
    Liu, Delong
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2020, 13 (01)
  • [26] Antibody response to BCMA in patients with multiple myeloma
    Bellucci, R
    Wu, CJ
    Chiaretti, S
    Alyea, EP
    Munshi, NC
    Ritz, J
    IMMUNOLOGY 2004: AUTOIMMUNITY, GENETIC AND DEGENERATIVE DISORDERS, MALIGNANCIES, AND TRANSPLANTATION, 2004, : 355 - 359
  • [27] BCMA-targeted immunotherapy for multiple myeloma
    Bo Yu
    Tianbo Jiang
    Delong Liu
    Journal of Hematology & Oncology, 13
  • [28] An APRIL-based chimeric antigen receptor for dual targeting of BCMA and TACI in multiple myeloma
    Lee, Lydia
    Draper, Benjamin
    Chaplin, Neil
    Philip, Brian
    Chin, Melody
    Galas-Filipowicz, Daria
    Onuoha, Shimobi
    Thomas, Simon
    Baldan, Vania
    Bughda, Reyisa
    Maciocia, Paul
    Kokalaki, Eva
    Neves, Margarida P.
    Patel, Dominic
    Rodriguez-Justo, Manuel
    Francis, James
    Yong, Kwee
    Pule, Martin
    BLOOD, 2018, 131 (07) : 746 - 758
  • [29] BCMA-targeting chimeric antigen receptor T-cell therapy for multiple myeloma
    Yang, Jinrong
    Zhou, Weilin
    Li, Dan
    Niu, Ting
    Wang, Wei
    CANCER LETTERS, 2023, 553
  • [30] BCMA CARs in multiple myeloma: room for more?
    Lee, Lydia Sarah Hui
    Yong, Kwee L.
    BLOOD, 2021, 137 (21) : 2859 - 2860