Postmortem Findings in Patient with Guillain-Barre Syndrome and Zika Virus Infection

被引:21
|
作者
Dirlikov, Emilio [1 ]
Torres, Jose V. [2 ]
Martines, Roosecelis Brasil [1 ]
Reagan-Steiner, Sarah [1 ]
Perez, George Venero [3 ]
Rivera, Aidsa [4 ]
Major, Chelsea [1 ,4 ]
Matos, Desiree [4 ]
Munoz-Jordan, Jorge [4 ]
Shieh, Wun-Ju [1 ]
Zaki, Sherif R. [1 ]
Sharp, Tyler M. [4 ,5 ]
机构
[1] Ctr Dis Control & Prevent, 1600 Clifton Rd NE,Mailstop E22, Atlanta, GA 30329 USA
[2] Puerto Rico Inst Forens Sci, San Juan, PR USA
[3] Hermanos Melendez Hosp, Bayamon, PR USA
[4] Ctr Dis Control & Prevent, San Juan, PR USA
[5] US Publ Hlth Serv Commissioned Corps, Rockville, MD USA
关键词
PUERTO-RICO; CASE SERIES; COLOMBIA;
D O I
10.3201/eid2401.171331
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Postmortem examination results of a patient with Guillain-Barre syndrome and confirmed Zika virus infection revealed demyelination of the sciatic and cranial IV nerves, providing evidence of the acute demyelinating inflammatory polyneuropathy Guillain-Barre syndrome variant. Lack of evidence of Zika virus in nervous tissue suggests that pathophysiology was antibody mediated without neurotropism.
引用
收藏
页码:114 / 117
页数:4
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