Fully packaged non-enzymatic glucose micro-sensor for in-vivo and continuously monitoring system applications

被引：0
|
作者：
Park, Dae J. [1 ]
Lee, Yi J. [1 ]
Park, Jae Y. [1 ]
机构：
[1] Kwangwoon Univ, Dept Elect Engn, Seoul 139701, South Korea
来源：
2007 IEEE SENSORS, VOLS 1-3 | 2007年
关键词：
D O I：
10.1109/ICSENS.2007.4388339
中图分类号：
TP18 [人工智能理论];
学科分类号：
081104 ; 0812 ; 0835 ; 1405 ;
摘要：
In this paper, fully packaged non-enzymatic glucose micro-sensor with Nafion membrane was designed and fabricated on silicon substrate for in-vivo applications. Working and counter electrodes of the micro-sensors were formed with electroplated mesoporous platinum and its reference electrode was patterned with screen-printed Ag/AgCl. The fabricated micro-sensors with plane Pt WE/CE, mesoporous Pt WE, and mesoporous Pt WE/CE have different sensitivities of 0.009 mu A mM(-1) cm(-2), 5.46 mu A mM(-1) cm(-2), and 7.75 mu A mM(-1) cm(-2) in glucose solution, respectively. The fully packaged micro-sensor with Nafion membrane has a sensitivity of 0.36 mu A mM(-1) cm(-2) and excellent linearity in the glucose concentration ranged from 0 mM to 30 mM. The biocompatible Nafion membrane was utilized to avoid not only reactivation of ascorbic acid and acetaminophen but also the electrode fouling by proteins in the blood serum for in-vivo and continuously monitoring systems.
引用
收藏
页码：75 / 78
页数：4
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