NOTCH1 Mutation in CLL Enhances Cell Cycle G1/S Transition through Specific Cyclin Overexpression: Preclinical Ground for CDK4/6 Targeted Inhibition

被引：1

作者：

Carrillo-Tornel, Salvador ^{[1
]}

Hua Chen-Liang, Tzu ^{[2
]}

Zurdo, Maria ^{[2
]}

Puiggros, Anna ^{[3
]}

Gomez-Llonin, Andrea ^{[4
]}

Garcia-Malo, Maria-Dolores ^{[5
]}

Cuenca, Ernesto J. ^{[6
]}

Jose Ortuno, Francisco ^{[7
]}

Hurtado Lopez, Ana M. ^{[8
]}

Espinet, Blanca ^{[9
]}

Jerez, Andres ^{[10
]}

机构：

[1] Hosp Morales Meseguer, CRH IMIB, Murcia, Spain

[2] Univ Murcia, IMIB, Ctr Reg Hemodonac, Hematol & Med Oncol Dept,Hosp Morales Meseguer, Murcia, Spain

[3] Hosp Mar, Serv Patol, Lab Citol Hematol & Citogenet, GRETNHE Inst Hosp Mar Invest Med IMIM, Barcelona, Spain

[4] Hosp Mar, Serv Patol, Lab Citogenet Mol, Barcelona, Spain

[5] Hosp Univ Morales Meseguer, Serv Hematol & Oncol Med, Murcia, Spain

[6] Univ Murcia, IMIB Arrixaca, Ctr Reg Hemodonac, Unidad Hematol & Oncol Med,Hosp Univ Morales Mese, Murcia, Spain

[7] Hosp Morales Meseguer, Hematol & Med Oncol Dept, IMIB, Murcia, Spain

[8] Univ Murcia, Hematol & Med Oncol Dept, Hosp Morales Meseguer, Murcia, Spain

[9] Hosp Mar IMIM, Grp Translat Res Hematol Neoplasms, Barcelona, Spain

[10] Univ Murcia, IMIB, Ctr Reg Hemodonac, Serv Hematol & Oncol Med,Hosp Univ Morales Mesegu, Murcia, Spain

来源：

BLOOD | 2021年 / 138卷

关键词：

D O I：

10.1182/blood-2021-152931

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

1544

引用

页数：4

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