NOTCH1 Mutation in CLL Enhances Cell Cycle G1/S Transition through Specific Cyclin Overexpression: Preclinical Ground for CDK4/6 Targeted Inhibition

被引：1
|
作者：
Carrillo-Tornel, Salvador [1 ]
Hua Chen-Liang, Tzu [2 ]
Zurdo, Maria [2 ]
Puiggros, Anna [3 ]
Gomez-Llonin, Andrea [4 ]
Garcia-Malo, Maria-Dolores [5 ]
Cuenca, Ernesto J. [6 ]
Jose Ortuno, Francisco [7 ]
Hurtado Lopez, Ana M. [8 ]
Espinet, Blanca [9 ]
Jerez, Andres [10 ]
机构：
[1] Hosp Morales Meseguer, CRH IMIB, Murcia, Spain
[2] Univ Murcia, IMIB, Ctr Reg Hemodonac, Hematol & Med Oncol Dept,Hosp Morales Meseguer, Murcia, Spain
[3] Hosp Mar, Serv Patol, Lab Citol Hematol & Citogenet, GRETNHE Inst Hosp Mar Invest Med IMIM, Barcelona, Spain
[4] Hosp Mar, Serv Patol, Lab Citogenet Mol, Barcelona, Spain
[5] Hosp Univ Morales Meseguer, Serv Hematol & Oncol Med, Murcia, Spain
[6] Univ Murcia, IMIB Arrixaca, Ctr Reg Hemodonac, Unidad Hematol & Oncol Med,Hosp Univ Morales Mese, Murcia, Spain
[7] Hosp Morales Meseguer, Hematol & Med Oncol Dept, IMIB, Murcia, Spain
[8] Univ Murcia, Hematol & Med Oncol Dept, Hosp Morales Meseguer, Murcia, Spain
[9] Hosp Mar IMIM, Grp Translat Res Hematol Neoplasms, Barcelona, Spain
[10] Univ Murcia, IMIB, Ctr Reg Hemodonac, Serv Hematol & Oncol Med,Hosp Univ Morales Mesegu, Murcia, Spain
来源：
BLOOD | 2021年 / 138卷
关键词：
D O I：
10.1182/blood-2021-152931
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1544
引用
收藏
页数：4
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