Facile synthesis of highly functionalized stable ketenimines via a three-component reaction

被引：16
|
作者：
Alizadch, Abdolali [1 ]
Rostamnia, Sadegh [1 ]
机构：
[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran
来源：
SYNTHESIS-STUTTGART | 2008年 / 01期
关键词：
isocyanides; oximes; ketenimines; multicomponent reactions; zwitterions;
D O I：
10.1055/s-2007-990894
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
It is shown that N-alkyl-substituted ketenimine derivatives can be efficiently prepared by the three-component coupling of electron-deficient alkynes, oximes, and isocyanides. The reaction is characterized by mild conditions, high selectivity, and tolerance to various functional groups. Yields are typically around 90%.
引用
收藏
页码：57 / 60
页数：4
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