Intravital imaging of host-parasite interactions in organs of the thoracic and abdominopelvic cavities

被引:5
|
作者
De Niz, Mariana [1 ,2 ]
Carvalho, Tania [2 ]
Penha-Goncalves, Carlos [3 ]
Agop-Nersesian, Carolina [1 ]
机构
[1] Univ Bern, Inst Cell Biol, Bern, Switzerland
[2] Univ Lisbon, Fac Med, Inst Med Mol Joao Lobo Antunes, Lisbon, Portugal
[3] Inst Gulbenkian Ciencias, Oeiras, Portugal
关键词
diseases; imaging; infection; intravital; microscopy; parasitology; IN-VIVO MICROSCOPY; MULTIPHOTON MICROSCOPY; MALARIA PARASITE; LIVER-STAGE; PLASMODIUM SPOROZOITES; CHONDROITIN SULFATE; PLACENTAL MALARIA; CELL INTERACTIONS; IMMUNE-RESPONSES; BLOOD-VESSELS;
D O I
10.1111/cmi.13201
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Infections with protozoan and helminthic parasites affect multiple organs in the mammalian host. Imaging pathogens in their natural environment takes a more holistic view on biomedical aspects of parasitic infections. Here, we focus on selected organs of the thoracic and abdominopelvic cavities most commonly affected by parasites. Parasitic infections of these organs are often associated with severe medical complications or have health implications beyond the infected individual. Intravital imaging has provided a more dynamic picture of the host-parasite interplay and contributed not only to our understanding of the various disease pathologies, but has also provided fundamental insight into the biology of the parasites.
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页数:21
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