Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome

被引:5
|
作者
Szydlowicz, Magdalena [1 ]
Krolak-Olejnik, Barbara [2 ]
Vargas, Sergio L. [3 ]
Zajaczkowska, Zaneta [1 ]
Paluszynska, Dorota [2 ]
Szczygiel, Anna [2 ]
Matos, Olga [4 ]
Hendrich, Andrzej B. [1 ]
Kicia, Marta [1 ]
机构
[1] Wroclaw Med Univ, Dept Biol & Med Parasitol, Ul J Mikulicza Radeckiego 9, PL-50345 Wroclaw, Poland
[2] Wroclaw Med Univ, Dept & Clin Neonatol, Wroclaw, Poland
[3] Univ Chile, Inst Ciencias Biomed, Fac Med, Santiago, Chile
[4] Univ Nova Lisboa, Inst Higiene & Med Trop, Unit Med Parasitol Global Hlth & Trop Med, Lisbon, Portugal
来源
JOURNAL OF INFECTIOUS DISEASES | 2021年 / 225卷 / 10期
关键词
Pneumocystis jirovecii; preterm infants; vertical transmission; respiratory distress syndrome; bronchopulmonary dysplasia;
D O I
10.1093/infdis/jiab209
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We describe the prevalence of Pneumocystis jirovecii in mother-infant pairs of very low birth weight newborns P. jirovecii in patients' specimens. Pneumocystis DNA was detected in 8 nasopharyngeal aspirates (14%) of 56 newborns and in 7 oral washes (21%) of 34 mothers. Pneumocystis detection immediately after birth suggests the possibility of its transplacental transmission. Compared to noncolonized infants, more frequent occurrence of bronchopulmonary dysplasia was seen in colonized infants (P = .02), suggesting a potential clinical importance of this pathogen in abnormal lung development.
引用
收藏
页码:1807 / 1810
页数:4
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