quantitative evaluation;
Parkinson's disease;
deep brain stimulation;
visual tracking test;
D O I:
10.1109/ICCME.2007.4382078
中图分类号:
R318 [生物医学工程];
学科分类号:
0831 ;
摘要:
Deep brain stimulation (DBS) is a effective treatment method for patients with Parkinson's disease (PD). In this study, a quantitative evaluation for the availability of DBS operation to PD patients were done by use of a visual tracking test. Visual target with random trajectory was adopted and the hand movement of three PD patients were recorded in the state before and after surgery. Parameters related to the tremor, rigidity, akinesia and so on were calculated and the effect of DBS operation was quantitatively evaluated. Remarkable improvement was validated through the parameters. In addition to the above analysis, comparison of the motor function between PD patients and normal healthy person was also investigated.
机构:
Boston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USABoston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USA
Wu, Chia-Chien
Cao, Bo
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机构:
Univ Alberta, Fac Med & Dent, Dept Psychiat, Edmonton, AB, CanadaBoston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USA
Cao, Bo
Dali, Veena
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机构:
Boston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USABoston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USA
Dali, Veena
Gagliardi, Celia
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机构:
Boston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USABoston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USA
Gagliardi, Celia
Barthelemy, Olivier J.
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机构:
Boston Univ, Dept Psychol & Brain Sci, Boston, MA 02215 USABoston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USA
Barthelemy, Olivier J.
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机构:
Salazar, Robert D.
Pomplun, Marc
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机构:
Univ Massachusetts, Dept Comp Sci, Boston, MA 02125 USABoston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USA
Pomplun, Marc
Cronin-Golomb, Alice
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机构:
Boston Univ, Dept Psychol & Brain Sci, Boston, MA 02215 USABoston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USA
Cronin-Golomb, Alice
Yazdanbakhsh, Arash
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机构:
Boston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USA
Boston Univ, Dept Psychol & Brain Sci, Boston, MA 02215 USABoston Univ, Ctr Computat Neurosci & Neural Technol, Boston, MA 02215 USA