Newer guidelines for the use of inhaled corticosteroids in chronic obstructive pulmonary disease (COPD) state that they should be reserved for those patients who are likely to derive the greatest benefits from this medication class. This makes the latest Global Initiative for Chronic Obstructive Lung disease (GOLD) guidelines of great importance. This article examines the utility of a previous diagnosis of asthma, the presence of eosinophilia, elevated immunoglobulin E, and positive bronchodilator response in identifying the people with COPD who also have asthma, and it presents two case studies of patients with COPD to illustrate the use of the GOLD guidelines in clinical practice.
机构:
Brigham & Womens Hosp, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA
Brigham & Womens Hosp, Div Gen Internal Med & Primary Care, 75 Francis St, Boston, MA 02115 USABrigham & Womens Hosp, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA
Castaldi, Peter J.
Vachani, Anil
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机构:
Perelman Sch Med, Dept Med, Philadelphia, PA USA
Corporal Michael J Crescenz Vet Adm Med Ctr, Philadelphia, PA USABrigham & Womens Hosp, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA