Optimization of Ultrasound-Assisted Extraction of Anthocyanins from Mulberry, Using Response Surface Methodology

被引：109
|
作者：
Zou, Tang-Bin [1 ]
Wang, Min [1 ]
Gan, Ren-You [1 ]
Ling, Wen-Hua [1 ,2 ]
机构：
[1] Sun Yat Sen Univ, Sch Publ Hlth, Dept Nutr, Guangzhou 510080, Guangdong, Peoples R China
[2] Guangdong Prov Key Lab Food, Guangzhou 510080, Guangdong, Peoples R China
来源：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2011年 / 12卷 / 05期
关键词：
ultrasound-assisted extraction; anthocyanins; mulberry; response surface methodology; ANTIOXIDANT ACTIVITY; INHIBITION; SEEDS; ACID; L;
D O I：
10.3390/ijms12053006
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Mulberry is one of the most widely used traditional Chinese medicines. Anthocyanins are the main bioactive components of mulberry, and possess important biological activities, such as antimicrobial, anti-inflammatory and antioxidant activities. This study investigated the ultrasound-assisted extraction (UAE) of anthocyanins from mulberry by using response surface methodology (RSM). The extraction conditions associated with anthocyanin yield, including extraction solvent, liquid-to-solid rate, temperature and extraction time, are discussed. The optimal conditions obtained by RSM for UAE from mulberry include 63.8% methanol contains 1% (v/v) trifluoroacetic acid (TFA), 43.2 degrees C temperature, 23.8 (v/w) liquid-to-solid ratio, and 40 min time for the maximum yield (64.70 +/- 0.45 mg/g). The results indicated that the UAE can be an effective method for the extraction of some active components from plant materials.
引用
收藏
页码：3006 / 3017
页数：12
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