Successful treatment of generalized granuloma annulare with adalimumab

We report the case of a 64year-old woman who demonstrated resolution of recalcitrant, generalized granuloma annulare (GA) following treatment with adalimumab. After showing little response to other treatment techniques, such as steroids and a triple antibiotic regimen, the patient was started on adalimumab. Within 3months, she showed almost complete resolution of lesions. Within 6months, she was completely lesion-free, and remained clear following 12months of adalimumab therapy. This case provides further evidence that tumour necrosis factor- inhibitors may be a treatment option for patients with recalcitrant, generalized GA.