DISRUPTION OF PD-L1 BY ENHANCED TWO-SGRNAS CRISPR/CAS9 IN TREATMENT OF GLIOBLASTOMA

被引：0
|
作者：
Fierro, Javier [1 ]
Perez, Joshua [1 ]
Aguilar, Rocio [1 ]
Dipasquale, Jake [1 ]
Tran, An
Factoriza, Chris [1 ]
Dou, Huanyu [1 ]
机构：
[1] Texas Tech Univ, Hlth Sci Ctr El Paso, El Paso, TX USA
来源：
NEURO-ONCOLOGY | 2021年 / 23卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
IMMU-37
引用
收藏
页码：100 / 100
页数：1
相关论文
共 50 条
  • [21] PD-L1 DISRUPTION BY CRISPR/Cas9-MEDIATED GENOME EDITING IN TUMOR CELLS PROMOTES ANTITUMOR IMMUNITY AND SUPPRESSES OVARIAN CANCER PROGRESSION IN MOUSE MODEL
    Yahata, T.
    Iwahashi, N.
    Mizoguchi, M.
    Toujima, S.
    Kaisho, T.
    Kondo, T.
    Ino, K.
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2018, 28 : 217 - 217
  • [22] CRISPR RNA Array-Guided Multisite Cleavage for Gene Disruption by Cas9 and Cpf1
    Wang, Dan
    Ma, Dejun
    Han, Jingxin
    Kong, Linghao
    Li, Lu-Yuan
    Xi, Zhen
    CHEMBIOCHEM, 2018, 19 (20) : 2195 - 2205
  • [23] Using a Dual CRISPR/Cas9 Approach to Gain Insight into the Role of LRP1B in Glioblastoma
    Peixoto, Joana
    Principe, Catarina
    Pestana, Ana
    Osorio, Hugo
    Pinto, Marta Teixeira
    Prazeres, Hugo
    Soares, Paula
    Lima, Raquel T.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (14)
  • [24] Genetic disruption of the KLF1 gene to overexpress the -globin gene using the CRISPR/Cas9 system
    Shariati, Laleh
    Khanahmad, Hossein
    Salehi, Mansoor
    Hejazi, Zahra
    Rahimmanesh, Ilnaz
    Tabatabaiefar, Mohammad Amin
    Modarressi, Mohammad Hossein
    JOURNAL OF GENE MEDICINE, 2016, 18 (10): : 294 - 301
  • [25] CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma
    Choi, Bryan D.
    Yu, Xiaoling
    Castano, Ana P.
    Darr, Henia
    Henderson, Daniel B.
    Bouffard, Amanda A.
    Larson, Rebecca C.
    Scarfo, Irene
    Bailey, Stefanie R.
    Gerhard, Genevieve M.
    Frigault, Matthew J.
    Leick, Mark B.
    Schmidts, Andrea
    Sagert, Jason G.
    Curry, William T.
    Carter, Bob S.
    Maus, Marcela, V
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7 (01):
  • [26] CRISPR/Cas9 disruption of UGT71L1 in poplar connects salicinoid and salicylic acid metabolism and alters growth and morphology
    Gordon, Harley
    Fellenberg, Christin
    Lackus, Nathalie D.
    Archinuk, Finn
    Sproule, Amanda
    Nakamura, Yoko
    Koellner, Tobias G.
    Gershenzon, Jonathan
    Overy, David P.
    Constabel, C. Peter
    PLANT CELL, 2022, 34 (08): : 2925 - 2947
  • [27] CRISPR/Cas9 targeted mutations of OsDSG1 gene enhanced salt tolerance in rice
    Linh Khanh Ly
    Tuong Manh Ho
    Thao Phuong Bui
    Linh Thi Nguyen
    Quyen Phan
    Ngoc Thu Le
    Luong Thi Mai Khuat
    Linh Hung Le
    Ha Hoang Chu
    Ngoc Bich Pham
    Phat Tien Do
    Functional & Integrative Genomics, 2024, 24
  • [28] CRISPR/Cas9 targeted mutations of OsDSG1 gene enhanced salt tolerance in rice
    Ly, Linh Khanh
    Ho, Tuong Manh
    Bui, Thao Phuong
    Nguyen, Linh Thi
    Phan, Quyen
    Le, Ngoc Thu
    Khuat, Luong Thi Mai
    Le, Linh Hung
    Chu, Ha Hoang
    Pham, Ngoc Bich
    Do, Phat Tien
    FUNCTIONAL & INTEGRATIVE GENOMICS, 2024, 24 (02)
  • [29] Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity
    Zhang, Shouyue
    Sun, Ao
    Qian, Jing-Mei
    Lin, Shuo
    Xing, Wenjing
    Yang, Yun
    Zhu, Han-Zhou
    Zhou, Xin-Yi
    Guo, Yan-Shuo
    Liu, Yun
    Meng, Yu
    Jin, Shu-Lin
    Song, Wenhao
    Li, Cheng-Ping
    Li, Zhaofu
    Jin, Shuai
    Wang, Jian-Hua
    Dong, Meng-Qiu
    Gao, Caixia
    Chen, Chunlai
    Bai, Yang
    Liu, Jun-Jie Gogo
    NATURE, 2024, : 484 - 492
  • [30] Lymphopenic condition enhanced the antitumor immunity of PD-1-knockout T cells mediated by CRISPR/Cas9 system in malignant melanoma
    Yang, Zike
    Wu, Huita
    Lin, Qing
    Wang, Xin
    Kang, Shijun
    IMMUNOLOGY LETTERS, 2022, 250 : 15 - 22
12345