Multi-contrast Photoacoustic Microscopy

被引：0
|
作者：
Hu, S. [1 ]
Sohn, R. [2 ]
Lu, Z. -H. [2 ]
Soetikno, B. [1 ]
Zhong, Q. [1 ]
Yao, J. [1 ]
Maslov, K. [1 ]
Arbeit, J. M. [2 ]
Wang, L. V. [1 ]
机构：
[1] Washington Univ, Dept Biomed Engn, St Louis, MO 63130 USA
[2] Washington Univ, Sch Med, Siteman Cancer Ctr, St Louis, MO 63130 USA
来源：
PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2012 | 2012年 / 8223卷
基金：
美国国家卫生研究院;
关键词：
Optical-resolution photoacoustic microscopy; vascular anatomy; hemoglobin oxygen saturation; oxygen extraction fraction; tumor microenvironment; IN-VIVO;
D O I：
10.1117/12.909754
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
We developed multi-contrast photoacoustic microscopy (PAM) for in vivo anatomical, functional, metabolic, and molecular imaging. This technical innovation enables comprehensive understanding of the tumor microenvironment. With multi-contrast PAM, we longitudinally determined tumor vascular anatomy, blood flow, oxygen saturation of hemoglobin, and oxygen extraction fraction.
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页数：4
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