Genome-Wide Association Mapping Identifies Novel Panicle Morphology Loci and Candidate Genes in Sorghum

被引:12
|
作者
Wang, Lihua [1 ]
Upadhyaya, Hari D. [2 ]
Zheng, Jian [1 ]
Liu, Yanlong [1 ]
Singh, Shailesh Kumar [2 ]
Gowda, C. L. L. [2 ]
Kumar, Rajendra [3 ]
Zhu, Yongqun [4 ]
Wang, Yi-Hong [5 ]
Li, Jieqin [1 ]
机构
[1] Anhui Sci & Technol Univ, Coll Agr, Chuzhou, Peoples R China
[2] Int Crops Res Inst Semi Arid Trop, Gene Bank, Patancheruvu, India
[3] ICAR Indian Agr Res Inst, Div Genet, New Delhi, India
[4] Sichuan Acad Agr Sci SAAS, Inst Agr Resources & Environm, Chengdu, Peoples R China
[5] Univ Louisiana Lafayette, Dept Biol, Lafayette, LA 70504 USA
来源
基金
中国国家自然科学基金;
关键词
sorghum; panicle morphology; association mapping; mini core; candidate genes; MINI-CORE COLLECTION; ARCHITECTURE; TRAITS; ABERRANT-PANICLE-ORGANIZATION-1; RESISTANCE; SIGNATURES; PROTEIN;
D O I
10.3389/fpls.2021.743838
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Panicle morphology is an important trait in racial classification and can determine grain yield and other agronomic traits in sorghum. In this study, we performed association mapping of panicle length, panicle width, panicle compactness, and peduncle recurving in the sorghum mini core panel measured in multiple environments with 6,094,317 single nucleotide polymorphism (SNP) markers. We mapped one locus each on chromosomes 7 and 9 to recurving peduncles and eight loci for panicle length, panicle width, and panicle compactness. Because panicle length was positively correlated with panicle width, all loci for panicle length and width were colocalized. Among the eight loci, two each were on chromosomes 1, 2, and 6, and one each on chromosomes 8 and 10. The two loci on chromosome 2, i.e., Pm 2-1 and Pm 2-2, were detected in 7 and 5 out of 11 testing environments, respectively. Pm 2-2 colocalized with panicle compactness. Candidate genes were identified from both loci. The rice Erect Panicle2 (EP2) ortholog was among the candidate genes in Pm 2-2. EP2 regulates panicle erectness and panicle length in rice and encodes a novel plant-specific protein with unknown functions. The results of this study may facilitate the molecular identification of panicle morphology-related genes and the enhancement of yield and adaptation in sorghum.
引用
收藏
页数:9
相关论文
共 50 条
  • [31] Genome-wide association identifies novel ROP risk loci in a multiethnic cohort
    Xiaohui Li
    Leah A. Owen
    Kent D. Taylor
    Susan Ostmo
    Yii-Der Ida Chen
    Aaron S. Coyner
    Kemal Sonmez
    M. Elizabeth Hartnett
    Xiuqing Guo
    Eli Ipp
    Kathryn Roll
    Pauline Genter
    R. V. Paul Chan
    Margaret M. DeAngelis
    Michael F. Chiang
    J. Peter Campbell
    Jerome I. Rotter
    Communications Biology, 7
  • [32] Genome-Wide Association Study in Chinese Children Identifies Novel Loci for Refraction
    Wang, Yuyao
    Zhang, Xiu Juan
    Pang, Calvin C. P.
    Yam, Jason C. S.
    Chen, Li Jia
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2024, 65 (07)
  • [33] Genome-Wide Association Study Identifies Novel Loci for Asthma in the UK Biobank
    Grant, Audrey V.
    Munter, Markus
    Ge, Bing
    Hocking, Toby
    Demenais, Florence
    Moffat, Miriam F.
    Cookson, William O.
    Pastinen, Tomi
    Sawcer, Stephen J.
    Lathrop, Mark
    GENETIC EPIDEMIOLOGY, 2016, 40 (07) : 614 - 614
  • [34] Genome-wide association study identifies novel breast cancer susceptibility loci
    Easton, Douglas F.
    Pooley, Karen A.
    Dunning, Alison M.
    Pharoah, Paul D. P.
    Thompson, Deborah
    Ballinger, Dennis G.
    Struewing, Jeffery P.
    Morrison, Jonathan
    Field, Helen
    Luben, Robert
    Wareham, Nicholas
    Ahmed, Shahana
    Healey, Catherine S.
    Bowman, Richard
    Meyer, Kerstin B.
    Haiman, Christopher A.
    Kolonel, Laurence K.
    Henderson, Brian E.
    Le Marchand, Loic
    Brennan, Paul
    Sangrajrang, Suleeporn
    Gaborieau, Valerie
    Odefrey, Fabrice
    Shen, Chen-Yang
    Wu, Pei-Ei
    Wang, Hui-Chun
    Eccles, Diana
    Evans, D. Gareth
    Peto, Julian
    Fletcher, Olivia
    Johnson, Nichola
    Seal, Sheila
    Stratton, Michael R.
    Rahman, Nazneen
    Chenevix-Trench, Georgia
    Bojesen, Stig E.
    Nordestgaard, Borge G.
    Axelsson, Christen K.
    Garcia-Closas, Montserrat
    Brinton, Louise
    Chanock, Stephen
    Lissowska, Jolanta
    Peplonska, Beata
    Nevanlinna, Heli
    Fagerholm, Rainer
    Eerola, Hannaleena
    Kang, Daehee
    Yoo, Keun-Young
    Noh, Dong-Young
    Ahn, Sei-Hyun
    NATURE, 2007, 447 (7148) : 1087 - U7
  • [35] Genome-wide association study of intraocular pressure identifies 83 novel loci
    Khawaja, Anthony P.
    Bailey, Jessica Cooke
    Simcoe, Mark James
    Igo, Robert P.
    Pasquale, Louis R.
    Foster, Paul J.
    Wiggs, Janey L.
    Hammond, Christopher J.
    Hysi, Pirro G.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2018, 59 (09)
  • [36] Genome-wide Association Study Identifies Novel Risk Loci for Apical Periodontitis
    Petty, Lauren E.
    Silva, Renato
    de Souza, Leticia Chaves
    Vieira, Alexandre R.
    Shaw, Douglas M.
    Below, Jennifer E.
    Letra, Ariadne
    JOURNAL OF ENDODONTICS, 2023, 49 (10) : 1276 - 1288
  • [37] Genome-Wide Association Study for Waldenstrom Macroglobulinemia Identifies Novel Susceptibility Loci
    McMaster, Mary L.
    Berndt, Sonja I.
    Zhang, Jianqing
    Slager, Susan L.
    Li, Shengchao
    Brown, Elizabeth E.
    Ekstrom-Smedby, Karin
    Kleinstern, Geffen
    Zhu, Bin
    Chung, Charles
    Burdette, Laurie
    Park, Ju-Hyun
    Birmann, Brenda M.
    Link, Brian K.
    McKay, James
    Monnereau, Alain
    Morton, Lindsay M.
    Nieters, Alexandra
    Smith, Alex
    Vermeulen, Roel
    Hjalgrim, Henrik
    Vajdic, Claire
    Teras, Lauren
    Hicks, Belynda
    Chatterjee, Nilanjan
    Rothman, Nathaniel
    Offit, Kenneth
    Cerhan, James R.
    Vijai, Joseph
    Goldin, Lynn R.
    Skibola, Christine F.
    Caporaso, Neil E.
    BLOOD, 2017, 130
  • [38] GENOME-WIDE ASSOCIATION STUDY IDENTIFIES NOVEL LOCI ASSOCIATED WITH BIPOLAR DISORDER
    Mullins, Niamh
    Pan, Gio
    Mattheisen, Manuel
    Trubetskoy, Vassily
    Ripke, Stephan
    Sloofman, Laura
    Charney, Alexander
    Stahl, Eli
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2019, 29 : 1089 - 1089
  • [39] Genome-wide association study identifies novel loci predisposing to cutaneous melanoma
    Amos, Christopher I.
    Wang, Li-E
    Lee, Jeffrey E.
    Gershenwald, Jeffrey E.
    Chen, Wei V.
    Fang, Shenying
    Kosoy, Roman
    Zhang, Mingfeng
    Qureshi, Abrar A.
    Vattathil, Selina
    Schacherer, Christopher W.
    Gardner, Julie M.
    Wang, Yuling
    Bishop, D. Tim
    Barrett, Jennifer H.
    MacGregor, Stuart
    Hayward, Nicholas K.
    Martin, Nicholas G.
    Duffy, David L.
    Mann, Graham J.
    Cust, Anne
    Hopper, John
    Brown, Kevin M.
    Grimm, Elizabeth A.
    Xu, Yaji
    Han, Younghun
    Jing, Kaiyan
    McHugh, Caitlin
    Laurie, Cathy C.
    Doheny, Kim F.
    Pugh, Elizabeth W.
    Seldin, Michael F.
    Han, Jiali
    Wei, Qingyi
    HUMAN MOLECULAR GENETICS, 2011, 20 (24) : 5012 - 5023
  • [40] Genome-wide association study identifies novel breast cancer susceptibility loci
    Douglas F. Easton
    Karen A. Pooley
    Alison M. Dunning
    Paul D. P. Pharoah
    Deborah Thompson
    Dennis G. Ballinger
    Jeffery P. Struewing
    Jonathan Morrison
    Helen Field
    Robert Luben
    Nicholas Wareham
    Shahana Ahmed
    Catherine S. Healey
    Richard Bowman
    Kerstin B. Meyer
    Christopher A. Haiman
    Laurence K. Kolonel
    Brian E. Henderson
    Loic Le Marchand
    Paul Brennan
    Suleeporn Sangrajrang
    Valerie Gaborieau
    Fabrice Odefrey
    Chen-Yang Shen
    Pei-Ei Wu
    Hui-Chun Wang
    Diana Eccles
    D. Gareth Evans
    Julian Peto
    Olivia Fletcher
    Nichola Johnson
    Sheila Seal
    Michael R. Stratton
    Nazneen Rahman
    Georgia Chenevix-Trench
    Stig E. Bojesen
    Børge G. Nordestgaard
    Christen K. Axelsson
    Montserrat Garcia-Closas
    Louise Brinton
    Stephen Chanock
    Jolanta Lissowska
    Beata Peplonska
    Heli Nevanlinna
    Rainer Fagerholm
    Hannaleena Eerola
    Daehee Kang
    Keun-Young Yoo
    Dong-Young Noh
    Sei-Hyun Ahn
    Nature, 2007, 447 : 1087 - 1093