Self-propelled liquid metal motors steered by a magnetic or electrical field for drug delivery

被引:133
|
作者
Zhang, Jie [1 ]
Guo, Rui [1 ]
Liu, Jing [1 ,2 ,3 ]
机构
[1] Tsinghua Univ, Dept Biomed Engn, Sch Med, Beijing 100084, Peoples R China
[2] Chinese Acad Sci, Tech Inst Phys & Chem, Beijing Key Lab Cryobiomed Engn, Beijing 100190, Peoples R China
[3] Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Cryogen, Beijing 100190, Peoples R China
关键词
CATALYTIC NANOMOTORS; OIL DROPLETS; MOTION; ELECTRONICS; MOVEMENT; OBJECTS; WATER; PUMP;
D O I
10.1039/c6tb00996d
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Self-propelled motors have inspired enormous potential in accomplishing various tasks when navigating in an aqueous environment due to their virtues of requiring no external energy source and autonomous locomotion. However, without reliable controllability, their potential value would be heavily reduced. Here, we demonstrate an innovative millimeter-scale self-propelled motor steered by an external magnetic or electric field, which successfully enables the motor to avoid out-of-control motion behavior encountered previously. A nickel cap is electroplated on a liquid metal droplet. The on-board fuel aluminum foil not only triggers the autonomous movement, but also enhances the adhesion between the nickel cap and the droplet. The current motor, composed of a nickel cap, aluminum and liquid metal, is capable of running with a velocity of 3 cm s(-1) for hours without the use of an external energy source. In addition, the integration of the nickel cap renders a magnetic field exploitable to easily alter the performance of the motor remotely. Furthermore, an external electrical field offers a feasible way to accelerate the motor directionally in a reliable manner. More importantly, as a conceptual experiment, when loaded with soft alginate-based biomaterial containing aluminium nanoparticles as drugs, such a motor is still able to be self-propelled, exhibiting steerable motion for drug delivery. The remarkable features of the liquid metal motor, such as softness, controllable self-propelled movement and drug-delivery application, represent a critical step toward functional intelligent soft robots or machines.
引用
收藏
页码:5349 / 5357
页数:9
相关论文
共 50 条
  • [31] Swarming of Self-propelled Particles on the Surface of a Thin Liquid Film
    Pototsky, Andrey
    Thiele, Uwe
    Stark, Holger
    CONTROL OF SELF-ORGANIZING NONLINEAR SYSTEMS, 2016, : 393 - 412
  • [32] Self-propelled droplet transport on shaped-liquid surfaces
    Gaby Launay
    Muhammad Subkhi Sadullah
    Glen McHale
    Rodrigo Ledesma-Aguilar
    Halim Kusumaatmaja
    Gary G. Wells
    Scientific Reports, 10
  • [33] Self-propelled Oil Droplets on Metal Surfaces during Electrodeposition
    Nakanishi, Shuji
    Nagai, Tomoyuki
    Ihara, Daisuke
    Nakato, Yoshihiro
    CHEMPHYSCHEM, 2008, 9 (16) : 2302 - 2304
  • [34] SELF-PROPELLED POTATO HARVESTER FOR FIELD-RESEARCH PLOTS
    LEDEBUHR, RL
    HANSEN, CM
    CHASE, R
    THOMPSON, N
    AMERICAN POTATO JOURNAL, 1978, 55 (07): : 382 - 382
  • [35] Numerical simulation for wellbore flow field of self-propelled nozzle
    Mo, Li
    Wang, Jun
    Zhongnan Daxue Xuebao (Ziran Kexue Ban)/Journal of Central South University (Science and Technology), 2015, 46 (10): : 3656 - 3662
  • [36] Optimal Control of a Self-propelled Particle in a Fluid Flow Field
    Abeysiriwardena, Singith
    Das, Tuhin
    2018 ANNUAL AMERICAN CONTROL CONFERENCE (ACC), 2018, : 4135 - 4140
  • [37] Self-propelled magnesium based micromotors: synthesis and magnetic steering
    Jin, Dongdong
    Yu, Jiangfan
    Chan, Ka Hei
    Zhang, Li
    INTERNATIONAL SYMPOSIUM OF OPTOMECHATRONICS TECHNOLOGY (ISOT 2015), 2015, 32
  • [38] Harvesting and In-Field Sorting of Citrus with a Self-Propelled Machine
    Gutierrez, A.
    Blasco, J.
    Chueca, P.
    Garcera, C.
    Alegre, S.
    Lopez, S.
    Cubero, S.
    Molto, E.
    I INTERNATIONAL SYMPOSIUM ON MECHANICAL HARVESTING AND HANDLING SYSTEMS OF FRUITS AND NUTS, 2012, 965 : 149 - 152
  • [39] Systems comparison of hydraulic and electrical traction drives in self-propelled harvesters
    Woebcke, Steffen
    Mirko, Lindner
    Herlitzius, Thomas
    CONFERENCE: AGRICULTURAL ENGINEERING: LAND - TECHNIK 2012 : MIT EAHRUNG UND INNOVATIONSKRAFT ZU MEHR EFFIZIENZ, 2012, 2173 : 321 - 328
  • [40] From One to Many: Dynamic Assembly and Collective Behavior of Self-Propelled Colloidal Motors
    Wang, Wei
    Duan, Wentao
    Ahmed, Suzanne
    Sen, Ayusman
    Mallouk, Thomas E.
    ACCOUNTS OF CHEMICAL RESEARCH, 2015, 48 (07) : 1938 - 1946