Regulation of β4 integrin expression by Rac1 is critical for the re-attachment of cancer cells to ECM and for metastasis

被引：0
|
作者：
Mori, Kazunori [1 ]
Ishikawa, Fumihiro [1 ]
Shibanuma, Motoko [1 ]
机构：
[1] Showa Univ, Sch Pharm, Div Canc Cell Biol, Tokyo, Japan
来源：
CANCER SCIENCE | 2018年 / 109卷
关键词：
Integrin; Rac;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P-3152
引用
收藏
页码：1044 / 1044
页数：1
相关论文
共 50 条
  • [31] Polo-like Kinase 4 Promotes Gastric Cancer Peritoneal Metastasis Through Activation of the Rac1 Gef PREX2
    Ng, Deanna
    Kazazian, Karineh
    Brashavitskaya, Olga
    Lee, Kiera
    Ali, Aiman
    Pacholczyk, Karina
    Luu, Shelly
    Brar, Savtaj
    Magalhaes, Marco
    Swallow, Carol Jane
    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2021, 233 (05) : E183 - E183
  • [32] Podocalyxin-like 1 promotes invadopodia formation and metastasis through activation of Rac1/Cdc42/cortactin signaling in breast cancer cells
    Lin, Cheng-Wei
    Sun, Min-Siou
    Liao, Mei-Ying
    Chung, Chu-Hung
    Chi, Yi-Hsuan
    Chiou, Li-Tin
    Yu, John
    Lou, Kuo-Lung
    Wu, Han-Chung
    CARCINOGENESIS, 2014, 35 (11) : 2425 - 2435
  • [33] Positive Feedback Regulation of Proliferation in Vascular Smooth Muscle Cells Stimulated by Lipopolysaccharide Is Mediated through the TLR 4/Rac1/Akt Pathway
    Jiang, Dehua
    Li, Dongye
    Cao, Lijuan
    Wang, Lele
    Zhu, Shasha
    Xu, Tongda
    Wang, Cheng
    Pan, Defeng
    PLOS ONE, 2014, 9 (03):
  • [34] Thymosin beta 4 induces colon cancer cell migration and clinical metastasis via enhancing ILK/IQGAP1/Rac1 signal transduction pathway
    Tang, Mei-Chuan
    Chan, Li-Chuan
    Yeh, Yi-Chen
    Chen, Cheng-Yu
    Chou, Teh-Ying
    Wang, Wei-Shu
    Su, Yeu
    CANCER LETTERS, 2011, 308 (02) : 162 - 171
  • [35] The critical role of SDF-1/CXCR4 axis in cancer and cancer stem cells metastasis
    S. Gelmini
    M. Mangoni
    M. Serio
    P. Romagnani
    E. Lazzeri
    Journal of Endocrinological Investigation, 2008, 31 : 809 - 819
  • [36] The critical role of SDF-1/CXCR4 axis in cancer and cancer stem cells metastasis
    Gellmini, S.
    Mangoni, M.
    Serio, M.
    Romagnani, P.
    Lazzeri, E.
    JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 2008, 31 (09) : 809 - 819
  • [37] Integrin β4 promotes DNA damage-related drug resistance in triple-negative breast cancer via TNFAIP2/IQGAP1/RAC1
    Fang, Huan
    Ren, Wenlong
    Cui, Qiuxia
    Liang, Huichun
    Yang, Chuanyu
    Liu, Wenjing
    Wang, Xinye
    Liu, Xue
    Shi, Yujie
    Feng, Jing
    Chen, Ceshi
    ELIFE, 2023, 12
  • [38] Integrin α5/β1 expression mediates HER-2 down-regulation in colon cancer cells
    Kuwada, SK
    Kuang, JQ
    Li, XF
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (19) : 19027 - 19035
  • [39] One enhancer stimulates cancer cells proliferation and metastasis via the regulation of PDL1 expression
    Li, Chunyan
    Chen, Han
    Liang, Han
    CANCER RESEARCH, 2018, 78 (13)
  • [40] Rac1-mediated sustained β4 integrin level develops reattachment ability of breast cancer cells after anchorage loss
    Mori, Kazunori
    Higurashi, Masato
    Ishikawa, Fumihiro
    Shibanuma, Motoko
    CANCER SCIENCE, 2021, 112 (08) : 3205 - 3217
12345