A triple-helix molecular switch photoelectrochemical biosensor for ultrasensitive microRNA detection based on position-controllable CdS//CdTe signal enhancement and switching

被引：18
|
作者：
Geng, Wenchao [1 ]
Yang, Ruiying [1 ,2 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
[2] Zhengzhou Univ, Coll Publ Hlth, Zhengzhou 450001, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 19期
关键词：
HYBRIDIZATION CHAIN-REACTION; ELECTROCHEMICAL APTASENSOR; QUANTUM DOTS; LABEL-FREE; ASSAY; AMPLIFICATION; STRATEGY; PROBES;
D O I：
10.1039/c9cc09877a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, a triple-helix molecular switch photoelectrochemical (PEC) biosensor is developed for ultrasensitive and selective detection of microRNA based on position-controllable CdS//CdTe signal enhancement and switching accompanying the signal amplification of a three-dimensional DNA walking machine. The developed PEC biosensor exhibits excellent analytical performance for microRNA-141 detection with a wide linear range from 5 aM to 100 fM, a low detection limit of 1.3 aM and outstanding selectivity.
引用
收藏
页码：2909 / 2912
页数：4
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  • [1] Triple-Helix Molecular Switch Electrochemical Ratiometric Biosensor for Ultrasensitive Detection of Nucleic Acids
    Xiong, Erhu
    Li, Zhenzhen
    Zhang, Xiaohua
    Zhou, Jiawan
    Yan, Xiaoxia
    Liu, Yunqing
    Chen, Jinhua
    [J]. ANALYTICAL CHEMISTRY, 2017, 89 (17) : 8830 - 8835
  • [2] Photoelectrochemical biosensor of HIV-1 based on cascaded photoactive materials and triple-helix molecular switch
    Wang, Shaopeng
    Zhao, Jinge
    Zhang, Yan
    Yan, Mei
    Zhang, Lina
    Ge, Shenguang
    Yu, Jinghua
    [J]. BIOSENSORS & BIOELECTRONICS, 2019, 139
  • [3] A versatile signal-on electrochemical biosensor for Staphylococcus aureus based on triple-helix molecular switch
    Cai, Rongfeng
    Zhang, Zhongwen
    Chen, Haohan
    Tian, Yaping
    Zhou, Nandi
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2021, 326
  • [4] A novel colorimetric triple-helix molecular switch aptasensor for ultrasensitive detection of tetracycline
    Ramezani, Mohammad
    Danesh, Noor Mohammad
    Lavaee, Parirokh
    Abnous, Khalil
    Taghdisi, Seyed Mohammad
    [J]. BIOSENSORS & BIOELECTRONICS, 2015, 70 : 181 - 187
  • [5] Ultrasensitive aptamer biosensor for arsenic (III) detection based on label-free triple-helix molecular switch and fluorescence sensing platform
    Pan, Jiafeng
    Li, Qiong
    Zhou, Danhua
    Chen, Junhua
    [J]. TALANTA, 2018, 189 : 370 - 376
  • [6] Triple-Helix Molecular Switch Triggered Cleavage Effect of DNAzyme for Ultrasensitive Electrochemical Detection of Chloramphenicol
    Wang, Senyao
    He, Baoshan
    Ren, Wenjie
    Suo, Zhiguang
    Xu, Yiwei
    Wei, Min
    Jin, Huali
    [J]. ACS APPLIED MATERIALS & INTERFACES, 2022, 14 (21) : 24681 - 24689
  • [7] A sensitive and versatile "signal-on" electrochemical aptasensor based on a triple-helix molecular switch
    Wang, Xiuzhong
    Jiang, Aiwen
    Hou, Ting
    Li, Feng
    [J]. ANALYST, 2014, 139 (23) : 6272 - 6278
  • [8] Flexible photoelectrochemical biosensor for ultrasensitive microRNA detection based on concatenated multiplex signal amplification
    Zhao, Yuecan
    Xiang, Junzhu
    Cheng, Hao
    Liu, Xiaojuan
    Li, Feng
    [J]. BIOSENSORS & BIOELECTRONICS, 2021, 194
  • [9] A Novel Fluorescent Aptasensor for Arsenic(III) Detection Based on a Triple-Helix Molecular Switch
    Yuan, Min
    Yang, Ye
    Chau, Nguyen Thi Quynh
    Zhang, Qinqin
    Wu, Xiuxiu
    Chen, Jiaye
    Wu, Zhiwei
    Zhong, Heng
    Li, Yuanyuan
    Xu, Fei
    [J]. MOLECULES, 2023, 28 (05):
  • [10] Triple-helix molecular-switch-actuated exponential rolling circular amplification for ultrasensitive fluorescence detection of miRNAs
    Zhao, Yihan
    Wang, Yu
    Liu, Su
    Wang, Chonglin
    Liang, Jiaxu
    Li, Shasha
    Qu, Xiaonan
    Zhang, Rufeng
    Yu, Jinghua
    Huang, Jiadong
    [J]. ANALYST, 2019, 144 (17) : 5245 - 5253
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