NRG Oncology CC001 Neurocognitive Final Analysis: A Phase III Trial of Hippocampal Avoidance (HA) in Addition to Whole-Brain Radiotherapy (WBRT) Plus Memantine to Preserve Neurocognitive Function (NCF) in PatientsWith Brain Metastases (BM)

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作者：
Wefel, Jeffrey S.
Pugh, Stephanie
Gondi, Vinai
Brown, Paul D.
Tome, Wolfgang
Armstrong, Terri S.
Bruner, Deborah
Bovi, Joseph
Robinson, Cliff
Khuntia, Deepak
Grosshans, David
Konski, Andre
Roberge, David
Kundapur, Vijayananda
Devisetty, Kiran
Shah, Sunjay
Usuki, Kenneth
Anderson, Bethany
Mehta, Minesh P.
Kachnic, Lisa
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来源：
NEUROSURGERY | 2019年 / 66卷
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中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
642
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页码：137 / 138
页数：2
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  • [1] NRG Oncology CC001: A phase III trial of hippocampal avoidance (HA) in addition to whole-brain radiotherapy (WBRT) plus memantine to preserve neurocognitive function (NCF) in patients with brain metastases (BM).
    Gondi, Vinai
    Deshmukh, Snehal
    Brown, Paul D.
    Wefel, Jeffrey Scott
    Tome, Wolfgang
    Armstrong, Terri
    Bruner, Deborah
    Bovi, Joseph A.
    Robinson, Cliff Grant
    Khuntia, Deepak
    Grosshans, David R.
    Konski, Andre A.
    Roberge, David
    Kundapur, Vijayananda
    Devisetty, Kiran
    Shah, Sunjay A.
    Usuki, Kenneth
    Anderson, Bethany Marie
    Mehta, Minesh P.
    Kachnic, Lisa A.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [2] PRESERVATION OF NEUROCOGNITIVE FUNCTION (NCF) WITH HIPPOCAMPAL AVOIDANCE DURING WHOLE-BRAIN RADIOTHERAPY (WBRT) FOR BRAIN METASTASES: PRELIMINARY RESULTS OF PHASE III TRIAL NRG ONCOLOGY CC001
    Gondi, Vinai
    Pugh, Stephanie
    Brown, Paul D.
    Wefel, Jeffrey
    Gilbert, Mark
    Bovi, Joseph
    Robinson, Cliff
    Tammie, Benzinger
    Tome, Wolfgang
    Armstrong, Terri
    Bruner, Deborah
    Khuntia, Deepak
    Grosshans, David
    Konski, Andre
    Robidoux, Andre
    Kundapur, Vijayananda
    Devisetty, Kiran
    Shah, Sunjay
    Usuki, Kenneth
    Anderson, Bethany
    Stea, Baldassarre
    Yoon, Harold
    Li, Jing
    Laack, Nadia
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    Mehta, Minesh P.
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    Deshmukh, S.
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    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2018, 102 (05): : 1607 - 1607
  • [4] Significant Preservation of Neurocognitive Function (NCF) and Patient-Reported Symptoms with Hippocampal Avoidance (HA) during Whole-Brain Radiotherapy (WBRT) for Brain Metastases: Final Results of Nrg Oncology CC001
    Gondi, V.
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    Brown, P. D.
    Wefel, J. S.
    Tome, W. A.
    Armstrong, T. S.
    Bruner, D. W.
    Bovi, J. A.
    Robinson, C. G.
    Khuntia, D.
    Grosshans, D. R.
    Konski, A. A.
    Roberge, D.
    Kundapur, V.
    Devisetty, K.
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    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2019, 105 (01): : S12 - S13
  • [5] Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001
    Brown, Paul D.
    Gondi, Vinai
    Pugh, Stephanie
    Tome, Wolfgang A.
    Wefel, Jeffrey S.
    Armstrong, Terri S.
    Bovi, Joseph A.
    Robinson, Cliff
    Konski, Andre
    Khuntia, Deepak
    Grosshans, David
    Benzinger, Tammie L. S.
    Bruner, Deborah
    Gilbert, Mark R.
    Roberge, David
    Kundapur, Vijayananda
    Devisetty, Kiran
    Shah, Sunjay
    Usuki, Kenneth
    Anderson, Bethany Marie
    Stea, Baldassarre
    Yoon, Harold
    Li, Jing
    Laack, Nadia N.
    Kruser, Tim J.
    Chmura, Steven J.
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    Deshmukh, Snehal
    Mehta, Minesh P.
    Kachnic, Lisa A.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (10) : 1019 - +
  • [6] PRESERVATION OF NEUROCOGNITIVE FUNCTION & PATIENT-REPORTED SYMPTOMS WITH HIPPOCAMPAL AVOIDANCE (HA) DURING WHOLE-BRAIN RADIOTHERAPY (WBRT) FOR BRAIN METASTASES: LONG-TERM RESULTS OF NRG ONCOLOGY CC001
    Armstrong, Terri
    Deshmukh, Snehal
    Brown, Paul
    Gondi, Vinai
    Benzinger, Tammy
    Gilbert, Mark
    Tome, Wolfgang
    Wefel, Jeffrey
    Bruner, Deborah
    Roberge, David
    Kundapur, Vijayananda
    Devisetty, Kiran
    Shah, Sunjay
    Usuki, Kenneth
    Baschnagel, Andrew
    Stea, Baldassarre
    Yoon, Harold
    Li, Jing
    Laack, Nadia
    Mehta, Minesh
    Kachnic, Lisa
    [J]. NEURO-ONCOLOGY, 2019, 21 : 24 - 25
  • [7] Evaluating Heterogeneity of Hippocampal Avoidant Whole Brain Radiotherapy (HA-WBRT) Treatment Effect on Neurocognitive Function (NCF): Secondary Analysis of NRG-CC001
    Cherng, H. R. R.
    Sun, K.
    Bentzen, S. M.
    Gondi, V.
    Mehta, M. P.
    Mishra, M. V.
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2022, 114 (03): : S8 - S8
  • [8] IMPACT OF THE RATE OF RADIOGRAPHIC RESPONSE (RR) OF BRAIN METASTASES (BM) TO WHOLE BRAIN RADIATION THERAPY (WBRT) ON NEUROCOGNITIVE FUNCTION (NCF) ON NRG-CC001
    Devisetty, Kiran
    Pugh, Stephanie
    Brown, Paul
    Gondi, Vinai
    Wefel, Jeffrey
    Solanki, Abhishek
    Kalapparambath, Tomy
    Harmon, Grant
    Saripalli, Anjali
    Chou, Brian
    Venkatesulu, Bhanu Prasad
    Boike, Thomas
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    Roberge, David
    Bovi, Joseph
    Mcgee, Mackenzie
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    Baschnagel, Andrew
    Usuki, Kenneth
    Mehta, Minesh
    Kachnic, Lisa
    [J]. NEURO-ONCOLOGY, 2022, 24 : 197 - 197
  • [9] Hippocampal avoidance whole-brain radiotherapy without memantine in preserving neurocognitive function for brain metastases: a phase II blinded randomized trial
    Yang, Wen-Chi
    Chen, Ya-Fang
    Yang, Chi-Cheng
    Wu, Pei-Fang
    Chan, Hsing-Min
    Chen, Jenny Ling-Yu
    Chen, Guann-Yiing
    Cheng, Jason Chia-Hsien
    Kuo, Sung-Hsin
    Hsu, Feng-Ming
    [J]. NEURO-ONCOLOGY, 2021, 23 (03) : 478 - 486
  • [10] Estimation of Conditional Neurocognitive Function Failure (NCFF) Incidence in Patients Receiving Whole Brain Radiation Therapy (WBRT) for Brain Metastases (BM): Secondary Analysis of NRG CC001
    Cherng, H. R. R.
    Sun, K.
    Bentzen, S. M.
    Mishra, M. V.
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2023, 117 (02): : E94 - E94
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