Voxel-based, image source-independent 3D asymmetry quantification in the maxillofacial region

This study proposes a voxel-based method, independent of image sources, for the evaluation, quantification, symmetry ratio definitions, and assessment of the optimal symmetry plane. Craniomaxillofacial bones can be evaluated through their symmetry ratio and the optimal symmetry plane can be used as a guide for oral and maxillofacial surgical planning and reconstruction after the removal of facial tumors, or as a guide for orthognathic surgery in jaw correction. This quantification analysis technique can be used in growth tracing planning, pre- and post-surgical comparisons, and the planning of follow-up therapy.