Chemokines and Chemokine Receptors in susceptibility to HIV-1 infection and progression to AIDS

被引：1
|
作者：
Chatterjee, Animesh [1 ]
Rathore, Anurag [1 ]
Vidyant, Sanjukta [1 ]
Kakkar, Kavita [1 ]
Dhole, Tapan N. [1 ]
机构：
[1] Sanjay Gandhi Postgrad Inst Med Sci, Dept Microbiol, Lucknow 226014, UP, India
来源：
DISEASE MARKERS | 2012年 / 32卷 / 03期
关键词：
HIV-1; infection; Polymorphism; Chemokine receptor; Chemokines; IMMUNODEFICIENCY-VIRUS TYPE-1; CCR5 PROMOTER POLYMORPHISMS; LONG-TERM NONPROGRESSORS; GENE COPY NUMBER; DISEASE PROGRESSION; INCREASED FREQUENCY; CELLULAR-IMMUNITY; FUSION COFACTOR; SDF-1; CHEMOKINE; CXC CHEMOKINE;
D O I：
10.1155/2012/147148
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A multitude of host genetic factors plays a crucial role in susceptibility to HIV-1 infection and progression to AIDS, which is highly variable among individuals and populations. This review focuses on the chemokine-receptor and chemokine genes, which were extensively studied because of their role as HIV co-receptor or co-receptor competitor and influences the susceptibility to HIV-1 infection and progression to AIDS in HIV-1 infected individuals.
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收藏
页码：143 / 151
页数：9
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