Vaccines efficacy to SARS-CoV-2 variants require holistic knowledge of viral immunology and protein biochemistry

被引：4
|
作者：
Kumar, Sachin [1 ]
机构：
[1] Indian Inst Technol Guwahati, Dept Biosci & Bioengn, Gauhati 781039, India
来源：
HUMAN VACCINES & IMMUNOTHERAPEUTICS | 2021年 / 17卷 / 11期
关键词：
Variants; immunity; spike; receptor; biochemistry;
D O I：
10.1080/21645515.2021.1964318
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The article by Abdalla et al., published in the journal on 28 May 2021, raised a concern. The SARS-CoV-2 spike (S) protein is the major targeted surface glycoprotein in COVID-19 vaccines. Many mutations in the S protein of SARS-CoV-2 have been reported across the globe. The S protein plays a crucial role in the induction of neutralizing antibody and protective immunity against SARS-CoV-2 infection. The protein biochemistry and immunology, in addition to conventional virology, will help us to delineate the biology of SARS-CoV-2 variants.
引用
收藏
页码：4128 / 4130
页数：3
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