SARS-CoV-2 Variants and Vaccines

被引：261

作者：

Krause, Philip R. ^{[1
]}

Fleming, Thomas R. ^{[2
]}

Longini, Ira M. ^{[3
]}

Peto, Richard ^{[4
]}

Briand, Sylvie ^{[15
]}

Heymann, David L. ^{[7
]}

Beral, Valerie ^{[4
]}

Snape, Matthew D. ^{[5
,6
]}

Rees, Helen ^{[10
]}

Ropero, Alba-Maria ^{[15
]}

Balicer, Ran D. ^{[12
]}

Cramer, Jakob P. ^{[8
]}

Munoz-Fontela, Cesar ^{[13
]}

Gruber, Marion ^{[1
]}

Gaspar, Rogerio ^{[15
]}

Singh, Jerome A. ^{[9
,11
]}

Subbarao, Kanta ^{[14
]}

Van Kerkhove, Maria D. ^{[15
]}

Swaminathan, Soumya ^{[15
]}

Ryan, Michael J. ^{[15
]}

Henao-Restrepo, Ana-Maria ^{[15
]}

机构：

[1] US FDA, Off Vaccines Res & Review, Ctr Biol Evaluat & Res, Bldg 71,Rm 3234,10903 New Hampshire Ave, Silver Spring, MD 20993 USA

[2] Univ Washington, Dept Stat, Seattle, WA 98195 USA

[3] Univ Florida, Dept Biostat, Gainesville, FL USA

[4] Univ Oxford, Nuffield Dept Populat Hlth, Oxford, England

[5] Univ Oxford, Dept Paediat, Oxford Vaccine Grp, Oxford, England

[6] Oxford Biomed Res Ctr, Natl Inst Hlth Res, Oxford, England

[7] Chatham House, Global Hlth Programme, London, England

[8] Coalit Epidem Preparedness Innovat, London, England

[9] Univ KwaZulu Natal, Howard Coll, Sch Law, Durban, South Africa

[10] Wits Reprod Hlth & HIV Inst, Johannesburg, South Africa

[11] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[12] Clalit Hlth Serv, Clalit Res Inst, Innovat Div, Tel Aviv, Israel

[13] Bernhard Nocht Inst Trop Med, Hamburg, Germany

[14] Peter Doherty Inst Infect & Immun, WHO, Collaborating Ctr Reference & Res Influenza, Melbourne, Vic, Australia

[15] WHO, Geneva, Switzerland

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2021年 / 385卷 / 02期

关键词：

COVID-19;

D O I：

10.1056/NEJMsr2105280

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Viral variants of concern may emerge with dangerous resistance to the immunity generated by the current vaccines to prevent coronavirus disease 2019 (Covid-19). Moreover, if some variants of concern have increased transmissibility or virulence, the importance of efficient public health measures and vaccination programs will increase. The global response must be both timely and science based. Copyright © 2021 Massachusetts Medical Society.

引用

页码：179 / 186

页数：8

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