Facile Route to Novel Pyrazolo[3,4-d]pyrimidine, Imidazo[1,2-b] pyrazole, Pyrazolo[3,4-d][1,2,3]triazine, Pyrazolo[1,5-c][1,3,5]triazine and Pyrazolo[1,5-c][1,3,5]thiadiazine Derivatives

被引：12

作者：

Bondock, Samir ^{[1
,2
]}

Tarhoni, Abd El-Gaber ^{[1
]}

Fadda, Ahmed A. ^{[1
]}

机构：

[1] Mansoura Univ, Dept Chem, Fac Sci, ET-35516 Mansoura, Egypt

[2] King Khalid Univ, Dept Chem, Fac Sci, Abha 9004, Saudi Arabia

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2015年 / 52卷 / 02期

关键词：

EFFICIENT SYNTHESIS; 5-AMINOPYRAZOLES; THIAZOLE; CHEMISTRY;

D O I：

10.1002/jhet.2041

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A regioselective synthesis of novel pyrazolo[3,4-d]pyrimidines, imidazo[1,2-b]pyrazoles, pyrazolo[3,4-d][1,2,3]triazine, pyrazolo[1,5-c][1,3,5]triazine and pyrazolo[1,5-c][1,3,5]thiadiazine incorporating a thiazole moiety was described via the reactions of the versatile, readily accessible 5-amino-3-(phenylamino)-N-(4-phenylthiazol-2-yl)-1H-pyrazole-4-carboxamide (1) with each of DMF-DMA, phenylisothiocyanate, chloroacetyl chloride, phenacyl bromide, benzoylisothiocyanate and formalin, respectively. All structures of the newly synthesized compounds were elucidated by elemental analysis and spectral data.

引用

页码：346 / 351

页数：6

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