C-C coupling reactions of superstrong CF3 groups with C(sp2)-H bonds:: Reactivity and synthetic utility of zero-valent niobium catalyst

被引：30

作者：

Fuchibe, Kohei ^{[1
]}

Mitomi, Ken ^{[1
]}

Suzuki, Ryo ^{[1
]}

Akiyama, Takahiko ^{[1
]}

机构：

[1] Gakushuin Univ, Fac Sci, Dept Chem, Toshima Ku, Tokyo 1718588, Japan

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2008年 / 3卷 / 02期

关键词：

carbenoids; C-C coupling; C-F activation; C-H activation; niobium;

D O I：

10.1002/asia.200700333

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

It was found that zero-valent niobium is an efficient catalyst for the intramolecular C-C coupling reactions of o-aryl and o-alkenyl alpha,alpha,alpha-trifluorotoluene derivatives. The superstrong C-F bonds of CF3 groups and neighboring C(sp(2))-H bonds were doubly activated, and fluorenes and indenes were obtained in good yields. The niobium fluorocarbenoid species is proposed to be the key intermediate.

引用

页码：261 / 271

页数：11

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