A research note on Mendelian randomization and causal inference in criminology: promises and considerations

被引:5
|
作者
Boutwell, Brian B. [1 ,2 ]
Adams, Charleen D. [3 ]
机构
[1] Univ Mississippi, Sch Appl Sci, 84 Dormitory Row West, University, MS 38677 USA
[2] Univ Mississippi, John D Bower Sch Populat Hlth, Med Ctr, Jackson, MS 39216 USA
[3] Harvard Univ, Dept Environm Hlth, TH Chan Sch Publ Hlth, Pmgram Mol & Integrat Physiol Sci, Cambridge, MA 02138 USA
关键词
Causal inference; Genome-wide association studies; Instrumental variables; Mendelian randomization; Research note; NATURAL EXPERIMENT; CONSEQUENCES; BEHAVIOR;
D O I
10.1007/s11292-020-09436-9
中图分类号
DF [法律]; D9 [法律];
学科分类号
0301 ;
摘要
Objectives Here, we provide a brief overview of a technique that may hold promise for scholars working on key criminological and criminal justice topics. Methods We provide an abbreviated overview of Mendelian randomization (MR), a newer variant of instrumental variables analysis, facilitated by expanding genomic technology worldwide. Our goal is to offer readers, unacquainted with the topic, a quick checklist of key assumptions, considerations, shortcomings, and practical applications of the technique. Results The causal inference capabilities of the design seem poised to continue pushing modern crime science forward, assuming that careful attention is payed to key assumptions of the technique. Conclusions Researchers interested in causality as it relates to antisocial behaviors may benefit by the addition of MR to the toolkit alongside other data analysis tools. This strategy also offers an avenue for cross-collaboration with scientists working in other fields, thus expanding the breadth of expertise contributing to an important societal subject in crime.
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页码:171 / 182
页数:12
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