Targeting HSP90 with the novel inhibitor NW457 attenuates radioresistance of human glioblastoma cells

被引：0
|
作者：
Kinzel, L. [1 ]
Seidl, K. [1 ]
Winssinger, N. [2 ]
Friedl, A. A. [1 ]
Belka, C. [1 ]
Lauber, K. [1 ]
机构：
[1] Univ Munich, Radiat Oncol, Munich, Germany
[2] Univ Geneva, Organ Chem, Geneva, Switzerland
来源：
RADIOTHERAPY AND ONCOLOGY | 2014年 / 111卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
PD-0428
引用
收藏
页码：S170 / S171
页数：2
相关论文
共 50 条
  • [41] Identification of the Plant Compound Geraniin as a Novel Hsp90 Inhibitor
    Vassallo, Antonio
    Vaccaro, Maria Carmela
    De Tommasi, Nunziatina
    Dal Piaz, Fabrizio
    Leone, Antonella
    PLOS ONE, 2013, 8 (09):
  • [42] Inhibition of gastric tumor growth by a novel Hsp90 inhibitor
    Lu, Chunwan
    Liu, Di
    Jin, Jing
    Deokar, Hemantkumar
    Zhang, Yi
    Buolamwini, John K.
    Yu, Xiaoming
    Yan, Chunhong
    Chen, Xiaoguang
    BIOCHEMICAL PHARMACOLOGY, 2013, 85 (09) : 1246 - 1256
  • [43] Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β generates sensitivity to the Hsp90 inhibitor radicicol
    Millson, Stefan H.
    Truman, Andrew W.
    Racz, Attila
    Hu, Bin
    Panaretou, Barry
    Nuttall, James
    Mollapour, Mehdi
    Soeti, Csaba
    Piper, Peter W.
    FEBS JOURNAL, 2007, 274 (17) : 4453 - 4463
  • [44] A novel HSP90 inhibitor targeting the C-terminal domain attenuates trastuzumab resistance in HER2-positive breast cancer
    Park, Jung Min
    Kim, Yoon-Jae
    Park, Soeun
    Park, Minsu
    Farrand, Lee
    Nguyen, Cong-Truong
    Ann, Jihyae
    Nam, Gibeom
    Park, Hyun-Ju
    Lee, Jeewoo
    Kim, Ji Young
    Seo, Jae Hong
    MOLECULAR CANCER, 2020, 19 (01)
  • [45] HSP90 inhibitor, 17-DMAG, enhances radiosensitivity of human cancer cells
    Thuy Tran
    Feis, Steven
    Robles, Ana
    Varticovski, Lyuba
    Capala, Jacek
    CANCER RESEARCH, 2006, 66 (08)
  • [46] A novel HSP90 inhibitor targeting the C-terminal domain attenuates trastuzumab resistance in HER2-positive breast cancer
    Jung Min Park
    Yoon-Jae Kim
    Soeun Park
    Minsu Park
    Lee Farrand
    Cong-Truong Nguyen
    Jihyae Ann
    Gibeom Nam
    Hyun-Ju Park
    Jeewoo Lee
    Ji Young Kim
    Jae Hong Seo
    Molecular Cancer, 19
  • [47] Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells
    Mori, Masaki
    Hitora, Toshiaki
    Nakamura, Osamu
    Yamagami, Yoshiki
    Horie, Ryosuke
    Nishimura, Hideki
    Yamamoto, Tetsuji
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2015, 46 (01) : 47 - 54
  • [48] Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor
    Li, Ting
    Chen, Xin
    Dai, Xiao-Yang
    Wei, Bin
    Weng, Qin-Jie
    Chen, Xiuping
    Ouyang, De-Fang
    Yan, Ru
    Huang, Zhang-Jian
    Jiang, Hu-Lin
    Zhu, Hong
    Lu, Jin-Jian
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017, 330 : 65 - 73
  • [49] Hsp90 inhibitor as a sensitizer of cancer cells to different therapies
    Solarova, Zuzana
    Mojzis, Jan
    Solar, Peter
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2015, 46 (03) : 907 - 926
  • [50] Inhibition of HSP90 as a Strategy to Radiosensitize Glioblastoma: Targeting the DNA Damage Response and Beyond
    Orth, Michael
    Albrecht, Valerie
    Seidl, Karin
    Kinzel, Linda
    Unger, Kristian
    Hess, Julia
    Kreutzer, Lisa
    Sun, Na
    Stegen, Benjamin
    Nieto, Alexander
    Maas, Jessica
    Winssinger, Nicolas
    Friedl, Anna A.
    Walch, Axel K.
    Belka, Claus
    Zitzelsberger, Horst
    Niyazi, Maximilian
    Lauber, Kirsten
    FRONTIERS IN ONCOLOGY, 2021, 11
12345