MoS2 quantum dots as fluorescent probe for methotrexate detection

被引：5
|
作者：
Yang, Like [1 ]
Ge, Jia [1 ]
Ma, Demiao [1 ]
Tang, Jinlu [1 ]
Wang, Hongqi [2 ]
Li, Zhaohui [1 ]
机构：
[1] Zhengzhou Univ, Coll Chem, Sch Basic Med Sci, Zhengzhou 450001, Peoples R China
[2] Henan Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Zhengzhou, Peoples R China
来源：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2022年 / 279卷
基金：
中国国家自然科学基金;
关键词：
Methotrexate; MoS(2 )quantum dots; Inner filter effect; Fluorescence; Biosensor; HIGH-DOSE METHOTREXATE; FACILE SYNTHESIS; ELECTROCHEMICAL SENSOR; PHOTOLUMINESCENCE; 2,4,6-TRINITROPHENOL; QUANTIFICATION; URINE; HPLC;
D O I：
10.1016/j.saa.2022.121443
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
Herein, we developed a unique fluorescence biosensor for methotrexate assay based on MoS(2 )quantum dots, which were synthesized in one step using sodium molybdate and cysteine as raw materials. The fluorescence of MoS(2 )QDs could be quenched when encountered with methotrexate, which was attributed to the inner filter effect (IFE). Furthermore, this present IFE-based method showed the linearity between the MoS(2 )QDs fluorescence intensity and the methotrexate concentration in the range of 0.05-1 mu M with the LOD of 42 nM. The practical applicability of this strategy was successfully demonstrated by detecting methotrexate in real samples. Results indicated that the proposed method could be a promising sensing platform for methotrexate analysis.
引用
收藏
页数：6
相关论文
共 50 条
  • [31] MoS2 quantum dots: synthesis, properties and biological applications
    Guo, Yongming
    Li, Jianwei
    [J]. MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2020, 109
  • [32] Photoresponsivity Enhancement of Monolayer MoS2 by Silicon Quantum Dots
    Gu, Minseon
    Lee, Keun Wook
    Park, Beomjin
    Joo, Beom Soo
    Chang, Young Jun
    Park, Dong-Wook
    Han, Moonsup
    [J]. PHYSICA STATUS SOLIDI-RAPID RESEARCH LETTERS, 2023, 17 (10):
  • [33] MoS2 quantum dots for electrocatalytic N2 reduction
    Luo, Yaojing
    Shen, Peng
    Li, Xingchuan
    Guo, Yali
    Chu, Ke
    [J]. CHEMICAL COMMUNICATIONS, 2021, 57 (77) : 9930 - 9933
  • [34] Inlaid ReS2 Quantum Dots in Monolayer MoS2
    Wang, Ziqian
    Luo, Ruichun
    Johnson, Isaac
    Kashani, Hamzeh
    Chen, Mingwei
    [J]. ACS NANO, 2020, 14 (01) : 899 - 906
  • [35] Photoluminescent MoS2 and MoSe2 Quantum Dots for the Detection of Nitro-Organic Explosives
    Paria, Shashikana
    Maity, Prasenjit
    [J]. ACS APPLIED NANO MATERIALS, 2024, 7 (14) : 16516 - 16524
  • [36] Water-soluble MoS2 quantum dots as effective fluorescence probe for the determination of bilirubin in human fluids
    Shanmugaraj, Krishnamoorthy
    John, S. Abraham
    [J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2019, 215 : 290 - 296
  • [37] High sensitivity label-free detection of Fe3+ ion in aqueous solution using fluorescent MoS2 quantum dots
    Ma, Jian
    Yu, Haihu
    Jiang, Xin
    Luo, Zhuozhao
    Zheng, Yu
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2019, 281 : 989 - 997
  • [38] Production of carbon dots during the liquid phase exfoliation of MoS2 quantum dots
    Zhang, Weimin
    Du, Jinhong
    Liu, Zhibo
    Zhang, Dingdong
    Wei, Qinwei
    Liu, Haichao
    Ma, Wei
    Ren, Wencai
    Cheng, Hui-Ming
    [J]. CARBON, 2019, 155 : 243 - 249
  • [39] Carbon quantum dots as a turn-on fluorescent probe for the sensitive detection of Cd 2+
    Zhou, Yan
    Chen, Guoqing
    Ma, Chaoqun
    Yang, Taiqun
    Li, Lei
    Gu, Jiao
    Zhu, Chun
    Hu, Anqi
    Li, Xin
    Guan, Weinan
    Zhang, Wei
    [J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2024, 317
  • [40] Hydrophilic AgInZnS quantum dots as a fluorescent turn-on probe for Cd2+ detection
    Liu, Yongfeng
    Tang, Xiaosheng
    Deng, Ming
    Zhu, Tao
    Edman, Ludvig
    Wang, Jia
    [J]. JOURNAL OF ALLOYS AND COMPOUNDS, 2021, 864
12345