Present and future of stem cells for cardiovascular therapy

被引:11
|
作者
Sanchez, Pedro L. [1 ]
Villa, Adolfo [1 ]
Sanz, Ricardo [1 ]
Dominguez, Marta [1 ]
Ludwig, Ingrid [1 ]
Eugenia Fernandez, M. [1 ]
Fernandez-Aviles, Francisco [1 ]
机构
[1] Hosp Gen Univ Gregorio Maranon, Serv Cardiol, E-28007 Madrid, Spain
关键词
acute myocardial infarction; cardiovascular; chronic heart disease; efficacy; safety; stem cells;
D O I
10.1080/07853890701513746
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this review we summarize the available evidence regarding the application of stem cell therapy for human cardiovascular repair, going over the principal concepts that will help us understand the present and future of this therapy: first the different types of cells available in clinical practice, second the delivery approaches, and third highlighting the most important clinical studies and their efficacy and safety results. In addition, we also speculate on the value of current clinical data to gain an insight into the mechanism of stem cell-based cardiac repair and to design clinical trials in the future.
引用
收藏
页码:412 / 427
页数:16
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