Correlations in low-frequency BOLD fluctuations reflect cortico-cortical connections

被引:224
|
作者
Lowe, MJ [1 ]
Dzemidzic, M [1 ]
Lurito, JT [1 ]
Mathews, VP [1 ]
Phillips, MD [1 ]
机构
[1] Indiana Univ, Sch Med, Dept Radiol, Indianapolis, IN 46202 USA
关键词
functional magnetic resonance imaging; resting state correlation; physiologic noise; working memory; dorsolateral prefrontal cortex;
D O I
10.1006/nimg.2000.0654
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Cross-correlation of low-frequency temporal fluctuations (<0.08 Hz) was used to correlate widely separated anatomic regions during continuous performance of a spatial working memory task. The regions of highest correlation to right-hemisphere dorsolateral prefrontal cortex correspond to the regions of largest baseline signal change in a conventional block-style functional MRI paradigm. Additionally, it is shown that the correlations between elements of the functional network increase during performance of a task that activates the network when compared to a task that does not directly stimulate the functionally connected network. (C) 2000 Academic Press.
引用
收藏
页码:582 / 587
页数:6
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