Indole alkaloids from Tabernaemontana bovina

被引：14
|
作者：
Lien, TP
Ripperger, H
Porzel, A
Merzweiler, K
Van Sung, T
Adam, G
机构：
[1] Inst Plant Biochem, D-06120 Halle, Germany
[2] Natl Ctr Nat Sci & Technol Vietnam, Inst Chem, Hanoi, Vietnam
[3] Univ Halle Wittenberg, Inst Inorgan Chem, D-06120 Halle, Germany
来源：
PHYTOCHEMISTRY | 1998年 / 49卷 / 05期
关键词：
Tabernaemontana bovina; Apocynaceae; indole alkaloids; 3-oxomehranine; 14; alpha-15; beta-dihydroxy-N-methylaspidospermine;
D O I：
10.1016/S0031-9422(98)00127-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In addition to (-)-mehranine, hecubine, ibogaine, ibogaline, 19R-epi voacristine, 20-hydroxyconopharyngine and pedunculine the novel indole alkaloids 3-oxomehranine and 14 alpha,15 beta-dihydroxy-N-methylaspidospermine have been isolated from the leaves and stems of Tabernaemontana bovina. The structure of 3-oxomehranine has been assigned by NMR investigations, the structure of 14 alpha,15 beta-dihydroxy-N-methylaspidospermine by X-ray analysis and their absolute configurations by circular dichroism. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1457 / 1461
页数：5
相关论文
共 50 条
  • [31] Novel β-carboline indole alkaloids from the leaves of Tabernaemontana elegans
    Mansoor, T. A.
    Ramalhete, C.
    Molnar, J.
    Mulhovo, S.
    Ferreira, M. J. U.
    PLANTA MEDICA, 2009, 75 (09) : 975 - 976
  • [32] Two new monoterpenoid indole alkaloids from Tabernaemontana divaricata
    Yuwen, Huansha
    Yuan, Yuxi
    Hao, Xiaojiang
    He, Hongping
    Zhang, Yu
    NATURAL PRODUCT RESEARCH, 2019, 33 (15) : 2139 - 2144
  • [33] Monoterpene indole alkaloids with anticancer activity from Tabernaemontana species
    Goncalves, Bruno M. F.
    Duarte, Noelia
    Ramalhete, Catia
    Barbosa, Filipa
    Madureira, Ana Margarida
    Ferreira, Maria-Jose U.
    PHYTOCHEMISTRY REVIEWS, 2024,
  • [34] Biologically active indole and bisindole alkaloids from Tabernaemontana divaricata
    Kam, TS
    Pang, HS
    Lim, TM
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2003, 1 (08) : 1292 - 1297
  • [35] Diverse aspidosperma-type alkaloids from the leaves of Tabernaemontana bovina with anti-hepatoma activity
    Yu, Yang
    Wu, Jing
    Bao, Mei-Fen
    Schinnerl, Johann
    Cai, Xiang-Hai
    FITOTERAPIA, 2023, 169
  • [36] PHARMACOGNOSTICAL STUDIES OF TABERNAEMONTANA SPECIES .16. INDOLE ALKALOIDS FROM TABERNAEMONTANA-ELEGANS
    VANDERHEIJDEN, R
    BROUWER, RL
    VERPOORTE, R
    VANBEEK, TA
    HARKES, PAA
    SVENDSEN, AB
    PLANTA MEDICA, 1986, (02) : 144 - 147
  • [37] TERTIARY INDOLE ALKALOIDS OF TABERNAEMONTANA DICHOTOMA SEEDS
    PERERA, P
    SANDBERG, F
    VANBEEK, TA
    VERPOORTE, R
    PLANTA MEDICA, 1983, 49 (01) : 28 - 31
  • [38] New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata
    Xiang-Mei Li
    Xian-Jun Jiang
    Guo-Zhu Wei
    Li-Hua Ren
    Li-Xia Wang
    Xue-Lian Cheng
    Fei Wang
    Natural Products and Bioprospecting, 2019, 9 : 425 - 429
  • [39] New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata
    Li, Xiang-Mei
    Jiang, Xian-Jun
    Wei, Guo-Zhu
    Ren, Li-Hua
    Wang, Li-Xia
    Cheng, Xue-Lian
    Wang, Fei
    NATURAL PRODUCTS AND BIOPROSPECTING, 2019, 9 (06) : 425 - 429
  • [40] New vasorelaxant indole alkaloids, taberniacins A and B, from Tabernaemontana divaricata
    Hirasawa, Yusuke
    Dai, Xin
    Deguchi, Jun
    Hatano, Shota
    Sasaki, Tadahiro
    Ohtsuka, Ruri
    Nugroho, Alfarius Eko
    Kaneda, Toshio
    Morita, Hiroshi
    JOURNAL OF NATURAL MEDICINES, 2019, 73 (03) : 627 - 632
12345