Indole alkaloids from Tabernaemontana bovina

被引:14
|
作者
Lien, TP
Ripperger, H
Porzel, A
Merzweiler, K
Van Sung, T
Adam, G
机构
[1] Inst Plant Biochem, D-06120 Halle, Germany
[2] Natl Ctr Nat Sci & Technol Vietnam, Inst Chem, Hanoi, Vietnam
[3] Univ Halle Wittenberg, Inst Inorgan Chem, D-06120 Halle, Germany
关键词
Tabernaemontana bovina; Apocynaceae; indole alkaloids; 3-oxomehranine; 14; alpha-15; beta-dihydroxy-N-methylaspidospermine;
D O I
10.1016/S0031-9422(98)00127-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In addition to (-)-mehranine, hecubine, ibogaine, ibogaline, 19R-epi voacristine, 20-hydroxyconopharyngine and pedunculine the novel indole alkaloids 3-oxomehranine and 14 alpha,15 beta-dihydroxy-N-methylaspidospermine have been isolated from the leaves and stems of Tabernaemontana bovina. The structure of 3-oxomehranine has been assigned by NMR investigations, the structure of 14 alpha,15 beta-dihydroxy-N-methylaspidospermine by X-ray analysis and their absolute configurations by circular dichroism. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1457 / 1461
页数:5
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