Fast surface plasmon resonance imaging sensor using Radon transform

被引：33
|
作者：
Karabchevsky, A. [1 ]
Karabchevsky, S.
Abdulhalim, I.
机构：
[1] Ben Gurion Univ Negev, Dept Electro Opt Engn, IL-84105 Beer Sheva, Israel
来源：
SENSORS AND ACTUATORS B-CHEMICAL | 2011年 / 155卷 / 01期
关键词：
Surface plasmon resonance; Imaging; Radon transform; Biosensing; SENSITIVITY ENHANCEMENT;
D O I：
10.1016/j.snb.2010.12.012
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Surface plasmon resonance (SPR) imaging technique is proposed in which a diverging laser beam at given frequency was used to illuminate the entire sensor surface in Kretschmann-Raether configuration. A pattern of dark intensity line on bright background is observed corresponding to the SPR dip at an angular range depending on the refractive index of the adjacent analyte and monitored by a two-dimensional CCD detector. A novel Radon transform based detection algorithm for the SPR line pattern is proposed, which is non sensitive to the laser speckle noise and improves the accuracy. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码：361 / 365
页数：5
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