Quality assurance program for peripheral blood mononuclear cell Cryopreservation

被引：15
|
作者：
Weinberg, Adriana
Louzao, Raul
Mussi-Pinhata, Marisa M.
Cruz, Maria L. S.
Pinto, Jorge A.
Huff, Maria F.
de Castro, Andrea C.
Sucupira, Maria C.
Denny, Thomas N.
机构：
[1] Univ Colorado, Hlth Sci Ctr, Denver, CO 80202 USA
[2] Duke Univ, Raleigh, NC USA
[3] Univ Sao Paulo, Sao Paulo, Brazil
[4] Hosp Servidor Estadual, Rio De Janeiro, Brazil
[5] Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil
[6] Univ Fed Rio de Janeiro, Rio De Janeiro, Brazil
[7] Hosp Conceicao, Porto Alegre, RS, Brazil
[8] Univ Fed Sao Paulo, Sao Paulo, Brazil
来源：
CLINICAL AND VACCINE IMMUNOLOGY | 2007年 / 14卷 / 09期
关键词：
ANTIRETROVIRAL THERAPY; CLINICAL-TRIALS; MULTICENTER; VIABILITY; DISEASE;
D O I：
10.1128/CVI.00187-07
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Seven Brazilian sites participating in the Pediatric AIDS Clinical Trials Group international cryopreservation quality assurance pilot program cryopreserved and shipped peripheral blood mononuclear cells (PBMC) to a central U.S. laboratory for analysis. Cell viability and recovery significantly increased over time. A wet-laboratory training session conducted at the central laboratory significantly improved the quality of the cryopreserved PBMC.
引用
收藏
页码：1242 / 1244
页数：3
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