Observations on the DDQ oxidation of 1-acyldihydropyridines - A synthetic application

被引：0
|
作者：
Wallace, DJ [1 ]
Gibb, AD [1 ]
Cottrell, IF [1 ]
Kennedy, DJ [1 ]
Brands, KMJ [1 ]
Dolling, UH [1 ]
机构：
[1] Merck Sharp & Dohme Res Labs, Dept Proc Res, Hoddesdon EN11 9BU, Herts, England
来源：
SYNTHESIS-STUTTGART | 2001年 / 12期
关键词：
N-acyldihydropyridine; DDQ oxidation; Diels-Alder; hydroquinone ether;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A synthetic application of the rate difference in oxidation of regioisomerically substituted N-acyldihydropyridines is reported. This has allowed for isolation of pure 4-substituted pyridine isomers without the need for chromatography. Diels-Alder adducts between a dihydropyridine and DDQ were isolated and formation of novel hydroquinone ethers was also observed during some reactions.
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页码：1784 / 1789
页数：6
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