DEEP IMMUNE PHENOTYPING OF T LYMPHOCYTE SUBSETS IN SYSTEMIC SCLEROSIS PATHOPHYSIOLOGY AND FOLLOWING RESPONSE TO TARGETED CYTOTOXIC TREATMENT

被引:0
|
作者
Papadimitriou, T. I. [1 ]
Van Caam, A. [1 ]
Lemmers, J. [1 ]
He, X. [2 ]
Vitters, E. [1 ]
Koenders, M. [1 ]
Smeets, R. [2 ]
Vonk, M. [1 ]
Van der Kraan, P. [1 ]
Koenen, H. [2 ]
Thurlings, R. M. [1 ]
机构
[1] Radboud Univ Nijmegen, Rheumat Dis, Med Ctr, Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Lab Med Immunol, Med Ctr, Nijmegen, Netherlands
关键词
D O I
10.1136/annrheumdis-2022-eular.3976
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
AB0139
引用
收藏
页码:1199 / 1199
页数:1
相关论文
共 50 条
  • [41] Diversification and expansion of the EBV-reactive cytotoxic T lymphocyte repertoire following autologous haematopoietic stem cell transplant for multiple sclerosis
    Massey, Jennifer
    Artuz, Crisbel
    Dyer, Zoe
    Jackson, Katherine
    Khoo, Melissa
    Visweswaran, Malini
    Withers, Barbara
    Moore, John
    Ma, David
    Sutton, Ian
    CLINICAL IMMUNOLOGY, 2023, 254
  • [42] Treatment of a patient with severe systemic sclerosis (SSc) using CD19-targeted CAR T cells
    Bergmann, Christina
    Mueller, Fabian
    Distler, Joerg H. W.
    Gyoerfi, Andrea-Hermina
    Voelkl, Simon
    Aigner, Michael
    Kretschmann, Sascha
    Reimann, Hannah
    Harrer, Thomas
    Bayerl, Nadine
    Boeltz, Sebastian
    Wirsching, Andreas
    Taubmann, Jule
    Roesler, Wolf
    Spriewald, Bernd
    Wacker, Jochen
    Atzinger, Armin
    Uder, Michael
    Kuwert, Torsten
    Mackensen, Andreas
    Schett, Georg
    ANNALS OF THE RHEUMATIC DISEASES, 2023, 82 (08) : 1117 - 1120
  • [43] Cytotoxic T cell antigen 4 and the status of T cell activation in lung cancer: local vs. systemic immune response
    Kwiecien, Iwona
    Skirecki, Tomasz
    Polubiec-Kownacka, Malgorzata
    Dziedzic, Dariusz
    Domagala-Kulawik, Joanna
    EUROPEAN RESPIRATORY JOURNAL, 2017, 50
  • [44] Functional Immune-phenotyping in Fingolimod-treated Multiple Sclerosis Patients: Assessing Drug Effects and Treatment Response Biomarkers
    Ghadiri, M.
    Rezk, A.
    Li, R.
    Giacomini, P. S.
    Antel, J.
    Bar-Or, A.
    MULTIPLE SCLEROSIS JOURNAL, 2019, 25 (03) : 444 - 444
  • [45] Cytotoxic T lymphocyte epitopes from human heparanase can elicit a potent anti-tumor immune response in mice
    Xu-Dong Tang
    Guang-Ping Liang
    Chuan Li
    Ying Wan
    Ting Chen
    Ling Chen
    Song-Tao Yu
    Zhen Xiong
    Dian-Chun Fang
    Guo-Zheng Wang
    Shi-Ming Yang
    Cancer Immunology, Immunotherapy, 2010, 59 : 1041 - 1047
  • [46] Global stability of a general HTLV-I infection model with Cytotoxic T-Lymphocyte immune response and mitotic transmission
    Elaiw, A. M.
    Shflot, A. S.
    Hobiny, A. D.
    ALEXANDRIA ENGINEERING JOURNAL, 2023, 67 : 77 - 91
  • [47] Heat shock protein 70-HBsAg complex inducing antigen-specific cytotoxic T lymphocyte immune response
    彭明利
    任红
    许红梅
    陈敏
    凌宁
    卿玉玲
    中华肝脏病杂志, 2003, (05) : 16 - 19
  • [48] Multidimensional Deep T-cell Phenotyping Defines Immune Response in Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
    Rozenova, Krasimira
    El Daker, Sary
    Baik, Jeeyeon
    Zhu, Menglei
    Dogan, Ahmet
    Roshal, Mikhail
    Galera, Pallavi
    LABORATORY INVESTIGATION, 2023, 103 (03) : S1229 - S1230
  • [49] Cytotoxic T lymphocyte epitopes from human heparanase can elicit a potent anti-tumor immune response in mice
    Tang, Xu-Dong
    Liang, Guang-Ping
    Li, Chuan
    Wan, Ying
    Chen, Ting
    Chen, Ling
    Yu, Song-Tao
    Xiong, Zhen
    Fang, Dian-Chun
    Wang, Guo-Zheng
    Yang, Shi-Ming
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2010, 59 (07) : 1041 - 1047
  • [50] Alteration in follicular T helper cell subsets and cytokine production contributes to dysregulated humoral immune response in systemic lupus erythematosus
    Szabo, Krisztina
    Jambor, Ilona
    Tarr, Tunde
    Papp, Gabor
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 70 - 70