One-pot Sonogashira coupling, hydroamination of alkyne and intramolecular C-H arylation reactions toward the synthesis of indole-fused benzosultams

被引：7
|
作者：
Debnath, Sudarshan [1 ]
Mondal, Shovan [1 ]
机构：
[1] Syamsundar Coll, Dept Chem, Shyamsundar 713424, India
来源：
TETRAHEDRON LETTERS | 2018年 / 59卷 / 23期
关键词：
Benzosultams; Sonogashira coupling; Hydroamination; C-H arylation; Indole; REGIOSELECTIVE SYNTHESIS; CYCLIZATION; SULTAMS; INHIBITORS; ALKENES; AMINE;
D O I：
10.1016/j.tetlet.2018.04.081
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A one-pot Sonogashira coupling, hydroamination of alkyne and C-H arylation reactions for the synthesis of indole-fused benzosultams are described. This method allows access to a variety of indole-fused seven membered benzosultams in good to excellent yields. The free indolyl nitrogen containing indole-fused benzosultams are also prepared by this method. The structures of the synthesized compounds are confirmed by single crystal XRD studies. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2260 / 2263
页数：4
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