NMR methods for studying quadruplex nucleic acids

被引：106
|
作者：
da Silva, Mateus Webba [1 ]
机构：
[1] Univ Ulster, Sch Biomed Sci, Coleraine BT52 1SA, Londonderry, North Ireland
来源：
METHODS | 2007年 / 43卷 / 04期
关键词：
NMR; quadruplexes; trans-hydrogen bonds; residual dipolar couplings; dynamics; structure calculation;
D O I：
10.1016/j.ymeth.2007.05.007
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Solution NMR spectroscopy has traditionally played a central role in examining quadruplex structure, dynamics, and interactions. Here, an overview is given of the methods currently applied to structural, dynamics, thermodynamics, and kinetics studies of nucleic acid quadruplexes and associated cations. (c) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码：264 / 277
页数：14
相关论文
共 50 条
  • [21] Nmr spectroscopy of nucleic acids
    Kainosho, M
    Ono, AM
    Tate, S
    Ono, A
    FASEB JOURNAL, 1997, 11 (09): : A1122 - A1122
  • [22] Quadruplex-Templated and Catalyzed Ligation of Nucleic Acids
    Kankia, Besik
    CHEMBIOCHEM, 2021, 22 (07) : 1261 - 1267
  • [23] The application of click chemistry for targeting quadruplex nucleic acids
    Saha, Puja
    Panda, Deepanjan
    Dash, Jyotirmayee
    CHEMICAL COMMUNICATIONS, 2019, 55 (06) : 731 - 750
  • [24] G-quadruplex nucleic acids as therapeutic targets
    Balasubramanian, Shankar
    Neidle, Stephen
    CURRENT OPINION IN CHEMICAL BIOLOGY, 2009, 13 (03) : 345 - 353
  • [25] G-quadruplex nucleic acids and human disease
    Wu, Yuliang
    Brosh, Robert M., Jr.
    FEBS JOURNAL, 2010, 277 (17) : 3470 - 3488
  • [26] Structural Probes in Quadruplex Nucleic Acid Structure Determination by NMR
    Karsisiotis, Andreas Ioannis
    da Silva, Mateus Webba
    MOLECULES, 2012, 17 (11) : 13073 - 13086
  • [27] NMR methodology for the study of nucleic acids
    Zídek, L
    Stefl, R
    Sklenár, V
    CURRENT OPINION IN STRUCTURAL BIOLOGY, 2001, 11 (03) : 275 - 281
  • [28] Energetic aspects of Locked Nucleic Acids quadruplex association and dissociation
    Petraccone, Luigi
    Erra, Eva
    Randazzo, Antonio
    Giancola, Concetta
    BIOPOLYMERS, 2006, 83 (06) : 584 - 594
  • [29] Targeting G-quadruplex nucleic acids for cancer therapeutics
    Seimiya, Hiroyuki
    CANCER SCIENCE, 2022, 113
  • [30] Design of small molecule drugs targeting quadruplex nucleic acids
    Neidle, Stephen
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
12345