Synthesis of the derivatives of andrographolide for NO donor

被引：0

作者：

Xu, H ^{[1
]}

Huang, WL ^{[1
]}

Zhang, HB ^{[1
]}

Zhou, JP ^{[1
]}

机构：

[1] China Pharmaceut Univ, Ctr Drug Res, Nanjing 210009, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 25卷 / 11期

关键词：

mutual prodrug principle; andrographolide; NO donor; bioavailability;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The mutual prodrug principle was applied to andrographolide derivatives. Nine compounds of NO donors were synthesized in order to find out new medicines of high bioavailability and good anticancer effect. All the target compounds have been identified by H-1 NMR, C-13 NMR and MS spectra.

引用

页码：1386 / 1391

页数：6

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