Structure based design and molecular docking studies for phosphorylated tau inhibitors in Alzheimer's disease

被引：0
|
作者：
Pradeepkiran, J. A. [1 ]
Reddy, P. Hemachandra [1 ]
机构：
[1] Texas Tech Univ, Garrison Inst Aging, Hlth Sci Ctr, 3601 4th St,MS 9424, Lubbock, MS 79430 USA
来源：
JOURNAL OF ALZHEIMERS DISEASE | 2019年 / 72卷
关键词：
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
引用
收藏
页码：S22 / S22
页数：1
相关论文
共 50 条
  • [21] Plasma phosphorylated tau181 and neurodegeneration in Alzheimer's disease
    Hansson, Oskar
    Cullen, Nicholas
    Zetterberg, Henrik
    Blennow, Kaj
    Mattsson-Carlgren, Niklas
    ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY, 2021, 8 (01): : 259 - 265
  • [22] Is phosphorylated tau a good biomarker of synapse pathology in Alzheimer's disease?
    Saura, Carlos A.
    Parra-Damas, Arnaldo
    BRAIN COMMUNICATIONS, 2023, 5 (03)
  • [23] Phosphorylated Tau in the Taste Buds of Alzheimer's Disease Mouse Models
    Kim, Hyun Ji
    Kim, Bo Hye
    Kim, Dong Kyu
    Kim, Hanbin
    Choi, Sang-Hyun
    Kim, Dong-Hoon
    Choi, Myunghwan
    Mook-Jung, Inhee
    Jeong, Yong Taek
    Kwon, Obin
    EXPERIMENTAL NEUROBIOLOGY, 2024, 33 (04) : 202 - 214
  • [24] Reduction of phosphorylated tau during memantine treatment of Alzheimer's disease
    Gunnarsson, M. Degerman
    Kilander, L.
    Basun, H.
    Lannfelt, L.
    DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2007, 24 (04) : 247 - 252
  • [25] Development of Tau Aggregation Inhibitors for Alzheimer's Disease
    Bulic, Bruno
    Pickhardt, Marcus
    Schmidt, Boris
    Mandelkow, Eva-Maria
    Waldmann, Herbert
    Mandelkow, Eckhard
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (10) : 1741 - 1752
  • [26] The Earliest Tau Dysfunction in Alzheimer's Disease? Tau Phosphorylated at S422 as a Toxic Seed
    Voss, Kellen
    Koren, John, III
    Dickey, Chad A.
    AMERICAN JOURNAL OF PATHOLOGY, 2011, 179 (05): : 2148 - 2151
  • [27] Pharmacophore-based models for therapeutic drugs against phosphorylated tau in Alzheimer's disease
    Pradeepkiran, Jangampalli Adi
    Reddy, Arubala P.
    Reddy, P. Hemachandra
    DRUG DISCOVERY TODAY, 2019, 24 (02) : 616 - 623
  • [28] Design of a new potent Alzheimer's disease inhibitor based on QSAR, molecular docking and molecular dynamics investigations
    Khedraoui, Meriem
    Nour, Hassan
    Yamari, Imane
    Abchir, Oussama
    Errougui, Abdelkbir
    Chtita, Samir
    CHEMICAL PHYSICS IMPACT, 2023, 7
  • [29] "Turn-On" Quinoline-Based Fluorescent Probe for Selective Imaging of Tau Aggregates in Alzheimer's Disease: Rational Design, Synthesis, and Molecular Docking
    Elbatrawy, Ahmed A.
    Hyeon, Seung Jae
    Yue, Nan
    Osman, Essam Eldin A.
    Choi, Seung Hyeo
    Lim, Sungsu
    Kim, Yun Kyung
    Ryu, Hoon
    Cui, Mengchao
    Nam, Ghilsoo
    ACS SENSORS, 2021, 6 (06) : 2281 - 2289
  • [30] Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies
    de Ruyter, Frederique Hart J.
    Morrema, Tjado H. J.
    den Haan, Jurre
    Twisk, Jos W. R.
    de Boer, Johannes F.
    Scheltens, Philip
    Boon, Baayla D. C.
    Thal, Dietmar R.
    Rozemuller, Annemieke J.
    Verbraak, Frank D.
    Bouwman, Femke H.
    Hoozemans, Jeroen J. M.
    Netherlands Brain Bank
    ACTA NEUROPATHOLOGICA, 2022, 145 (2) : 197 - 218
12345