Synergic effect of doxorubicin release and two-photon irradiation of Mn2+-doped Prussian blue nanoparticles on cancer therapy

被引:10
|
作者
Ali, Lamiaa M. A. [1 ,2 ]
Mathlouthi, Emna [3 ,4 ]
Cahu, Maelle [3 ]
Sene, Saad [3 ]
Daurat, Morgane [1 ,5 ]
Long, Jerome [3 ]
Guari, Yannick [3 ]
Salles, Fabrice [3 ]
Chopineau, Joel [3 ]
Devoisselle, Jean-Marie [3 ]
Larionova, Joulia [3 ]
Gary-Bobo, Magali [1 ]
机构
[1] Univ Montpellier, CNRS, ENSCM, Inst Biomol Max Mousseron,UMR5247,Fac Pharm, 15 Ave Charles Flahault, F-34093 Montpellier 05, France
[2] Univ Alexandria, Med Res Inst, Dept Biochem, Alexandria, Egypt
[3] Univ Montpellier, Inst Charles Gerhardt, CNRS, ENSCM, Pl Eugene Bataillon, F-34095 Montpellier 5, France
[4] Univ Tunis El Manar, Fac Sci, UR 11 ES 19, Phys Chim Mat Etat Condense, Tunis 2092, Tunisia
[5] NanoMedSyn, 15 Ave Charles Flahault, F-34093 Montpellier, France
关键词
PHOTOTHERMAL THERAPY; IN-VITRO; POLYMER NANOPARTICLES; GOLD NANOPARTICLES; CHEMOTHERAPY; AGENTS; ULTRASMALL; ABLATION; DYES;
D O I
10.1039/c9ra09133e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We demonstrate here that Mn2+-doped Prussian blue nanoparticles of ca. 55 nm loaded with doxorubicin may be used as efficient therapeutic agents for combined photothermal and chemo-therapy of cancer cells with a synergic effect under two photon irradiation.
引用
收藏
页码:2646 / 2649
页数:4
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