Synergic effect of doxorubicin release and two-photon irradiation of Mn2+-doped Prussian blue nanoparticles on cancer therapy

被引：10

作者：

Ali, Lamiaa M. A. ^{[1
,2
]}

Mathlouthi, Emna ^{[3
,4
]}

Cahu, Maelle ^{[3
]}

Sene, Saad ^{[3
]}

Daurat, Morgane ^{[1
,5
]}

Long, Jerome ^{[3
]}

Guari, Yannick ^{[3
]}

Salles, Fabrice ^{[3
]}

Chopineau, Joel ^{[3
]}

Devoisselle, Jean-Marie ^{[3
]}

Larionova, Joulia ^{[3
]}

Gary-Bobo, Magali ^{[1
]}

机构：

[1] Univ Montpellier, CNRS, ENSCM, Inst Biomol Max Mousseron,UMR5247,Fac Pharm, 15 Ave Charles Flahault, F-34093 Montpellier 05, France

[2] Univ Alexandria, Med Res Inst, Dept Biochem, Alexandria, Egypt

[3] Univ Montpellier, Inst Charles Gerhardt, CNRS, ENSCM, Pl Eugene Bataillon, F-34095 Montpellier 5, France

[4] Univ Tunis El Manar, Fac Sci, UR 11 ES 19, Phys Chim Mat Etat Condense, Tunis 2092, Tunisia

[5] NanoMedSyn, 15 Ave Charles Flahault, F-34093 Montpellier, France

来源：

RSC ADVANCES | 2020年 / 10卷 / 05期

关键词：

PHOTOTHERMAL THERAPY; IN-VITRO; POLYMER NANOPARTICLES; GOLD NANOPARTICLES; CHEMOTHERAPY; AGENTS; ULTRASMALL; ABLATION; DYES;

D O I：

10.1039/c9ra09133e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We demonstrate here that Mn2+-doped Prussian blue nanoparticles of ca. 55 nm loaded with doxorubicin may be used as efficient therapeutic agents for combined photothermal and chemo-therapy of cancer cells with a synergic effect under two photon irradiation.

引用

页码：2646 / 2649

页数：4

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