Coma With Absent Brainstem Reflexes Resulting From Zolpidem Overdose

被引：53

作者：

Kuzniar, Tomasz J. ^{[2
]}

Balagani, Rajesh ^{[1
]}

Radigan, Kathryn A. ^{[1
]}

Factor, Phillip ^{[3
]}

Mutlu, Goekhan M. ^{[2
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Div Pulm & Crit Care Med, Chicago, IL 60611 USA

[2] NorthShore Univ HealthSyst, Div Pulm & Crit Care Med, Evanston, IL USA

[3] Columbia Univ, Coll Physicians & Surg, Div Pulm Allergy & Crit Care Med, New York, NY USA

来源：

AMERICAN JOURNAL OF THERAPEUTICS | 2010年 / 17卷 / 05期

关键词：

zolpidem; overdose; suicide; coma; brainstem; glasgow comascale; depression; respiratory failure; SEDATIVE DRUGS; DEATH; INTOXICATION;

D O I：

10.1097/MJT.0b013e318188bdca

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Zolpidem is a nonbenzodiazepine hypnotic with a favorable adverse effect profile. There are single reports of respiratory decompensation associated with zolpidem overdose. We report a case of a young woman with depression who developed deep coma with respiratory failure and a loss of brainstem reflexes as a result of zolpidem overdose. Supportive management led to a complete recovery of neurologic function. Acute zolpidem overdose should be considered in the differential diagnosis of coma with absent brainstem reflexes.

引用

页码：E172 / E174

页数：3

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