Highly selective tridentate fluorescent probes for visualizing intracellular Mg2+ dynamics without interference from Ca2+ fluctuation

被引：24
|
作者：
Matsui, Yusuke [1 ]
Sadhu, Kalyan K. [1 ]
Mizukami, Shin [2 ]
Kikuchi, Kazuya [1 ,3 ]
机构：
[1] Osaka Univ, Grad Sch Engn, Dept Mat & Life Sci, Suita, Osaka 5650871, Japan
[2] Tohoku Univ, Inst Multidisciplinary Res Adv Mat, Sendai, Miyagi 9808577, Japan
[3] Osaka Univ, WPI Immunol Frontier Res Ctr, Suita, Osaka 5650871, Japan
来源：
CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 77期
关键词：
LIVING CELLS; MAGNESIUM; INDICATORS; SENSORS; DESIGN;
D O I：
10.1039/c7cc06141b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We developed highly selective fluorescent Mg2+ probes based on a novel tridentate Mg2+-selective chelator. The superior selectivity for Mg2+ over Ca2+ enabled the detection of intracellular Mg2+ concentration changes without any response to Ca2+ influx. The new probes are potential keys to elucidating intracellular Mg2+ dynamics under conditions of extremely sharp Ca2+ fluctuation.
引用
收藏
页码：10644 / 10647
页数：4
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