Graphical interpretation of non-negative factorization expecting bio-Raman research

被引：1
|
作者：
Yu, Hua [1 ]
Wang, Ziteng [1 ]
Nemoto, Mana [2 ]
Suzuta, Kazuyuki [3 ]
Ito, Len [3 ]
Morita, Shin-ichi [1 ]
机构：
[1] Tohoku Univ, Grad Sch Sci, Aoba Ku, 6-3 Aramaki Aza Aoba, Sendai, Miyagi 9808578, Japan
[2] Tohoku Univ, Grad Sch Engn, Aoba Ku, 6-6 Aramaki Aza Aoba, Sendai, Miyagi 9808579, Japan
[3] Milbon, Res & Dev Dept, Miyakojima Ku, 2-3-35 Zengenji Cho, Osaka, Osaka 5340015, Japan
来源：
APPLIED PHYSICS EXPRESS | 2021年 / 14卷 / 08期
关键词：
non-negative matrix factorization; NMF; bio; Raman; spectra; BACKGROUND REMOVAL; IN-VIVO; CELLS; SENSITIVITY; DYNAMICS;
D O I：
10.35848/1882-0786/ac0fb7
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
Non-negative matrix factorization (NMF) has been frequently used in research on live cells, biomolecules, and tissues (bio-Raman research) to disentangle the complicated and large sized data. A stagnation is that NMF does not provide unique decomposition, depending on initial settings; that is, NMF returns non-negative spectral components close to the truths, but solely giving several possibilities. In this research, we visualized possible ranges of NMF in binary component system. The mechanism of NMF became more clarified and opened new viewpoints.
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页数：4
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