The HIV/HCV-Coinfected Patient and New Treatment Options

被引：6
|
作者：
Vachon, Marie-Louise C. [1 ,2 ]
Dieterich, Douglas T. [1 ]
机构：
[1] Mt Sinai Sch Med, Div Liver Dis, New York, NY 10029 USA
[2] Mt Sinai Sch Med, Div Infect Dis, New York, NY 10029 USA
来源：
CLINICS IN LIVER DISEASE | 2011年 / 15卷 / 03期
关键词：
HIV; Hepatitis C; Coinfection; Treatment; Direct-acting antivirals; CHRONIC HEPATITIS-C; INTERFERON PLUS RIBAVIRIN; SUSTAINED VIROLOGICAL RESPONSE; HIV-INFECTED PATIENTS; HUMAN-IMMUNODEFICIENCY-VIRUS; INSULIN-RESISTANCE; LIVER FIBROSIS; PEGYLATED INTERFERON-ALPHA-2B; ANTIRETROVIRAL THERAPY; PROTEASE INHIBITORS;
D O I：
10.1016/j.cld.2011.05.006
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Hepatitis C (HCV) treatment is on the cusp of change with the approval of the first direct-acting antivirals: telaprevir and boceprevir. Drug-drug interactions with HIV antiretrovirals, increased toxicity, and rapid selection of HCV-resistant mutants are among the treatment complexities expected in this difficult-to-treat population. Until the current standard of care changes, focus should be on strategies to optimize management of HIV/HCV-coinfected patients with currently available options. This article reviews the latest predictive factors of response to HCV treatment with the current standard of care in HIV-coinfected patients, and new treatment options.
引用
收藏
页码：585 / +
页数：14
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