Deacetylravidomycin M, a new inhibitor of IL-4 signal transduction, produced by Streptomyces sp WK-6326 -: II.: Structure elucidation

被引：9
|
作者：
Arai, M
Tomoda, H
Tabata, N
Ishiguro, N
Kobayashi, S
Omura, S [1 ]
机构：
[1] Kitasato Univ, Kitasato Inst, Minato Ku, Tokyo 1088642, Japan
[2] Kitasato Univ, Kitasto Inst Life Sci, Minato Ku, Tokyo 1088642, Japan
[3] Sci Univ Tokyo, Fac Pharmaceut Sci, Shinjuku Ku, Tokyo 1620826, Japan
来源：
JOURNAL OF ANTIBIOTICS | 2001年 / 54卷 / 07期
关键词：
D O I：
10.7164/antibiotics.54.562
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The structure of deacetylravidomycin M, an inhibitor of interleukin-4 signal transduction, was elucidated to be 6H-benzo[d]naphtho[1,2-b]pyran-6-one. 4-[3,6-dideoxy-3-(dimethylamino)-alpha -altropyranosyl]-1-hydroxy-10,12-dimethoxy-8-methyl- by spectroscopic studies including NMR measurements.
引用
收藏
页码：562 / 566
页数：5
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