Stem-cell transplantation in patients with germ cell tumors

被引:0
|
作者
Linkesch, W [1 ]
机构
[1] Graz Univ, Med Klin, Klin Abt Hamatol, A-8036 Graz, Austria
关键词
germ cell tumor; stem-cell transplantation; high-dose chemotherapy;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
High dose chemotherapy (HDCT) with autologous stem cell transplantation in patients with relapsed or refractory non-seminomatous germ cell tumors seems to be the only therapeutic option with curative intention. Evaluation of a scored risk profile before HDCT might significantly support the precise estimation of results after HDCT. Patients with a negative or low score could achieve long-lasting complete remissions or might be cured, whereas patients with absolutely refractory disease do not benefit from HDCT. Ongoing prospective randomised trials in Europe and USA comparing standardtherapy with KDCT will hopefully contribute to the right therapeutic decision in the future.
引用
收藏
页码:30 / 32
页数:3
相关论文
共 50 条
  • [21] Peripheral stem-cell transplantation
    Kumar, L
    Gulati, SC
    LANCET, 1995, 346 : S9 - S9
  • [22] INUTERO STEM-CELL TRANSPLANTATION
    GOLBUS, MS
    AMERICAN JOURNAL OF HUMAN GENETICS, 1991, 49 (04) : 32 - 32
  • [23] Fetal stem-cell transplantation
    Tiblad, Eleonor
    Westgren, Magnus
    BEST PRACTICE & RESEARCH IN CLINICAL OBSTETRICS & GYNAECOLOGY, 2008, 22 (01): : 189 - 201
  • [24] HIGH-DOSE CARBOPLATIN, ETOPOSIDE AND IFOSFAMIDE FOLLOWED BY AUTOLOGOUS STEM-CELL TRANSPLANTATION IN POOR RISK GERM-CELL TUMORS
    SIEGERT, W
    BEYER, J
    STROHSCHEER, I
    WEISBACH, V
    HEUFT, HG
    OETTLE, H
    ZINGSEM, J
    ECKSTEIN, R
    SCHMOLL, HJ
    HUHN, D
    BONE MARROW TRANSPLANTATION, 1992, 10 : 26 - 26
  • [25] Stem-Cell Transplantation for Sickle Cell Disease
    Dew, Alexander
    van Besien, Koen
    NEW ENGLAND JOURNAL OF MEDICINE, 2010, 362 (10): : 955 - 955
  • [26] STEM-CELL PROCUREMENT AND TRANSPLANTATION IN PEDIATRIC-PATIENTS
    HOCKER, P
    EMMINGER, W
    PETERS, C
    TRANSFUSION SCIENCE, 1994, 15 (04): : 339 - 342
  • [27] ENGRAFTMENT KINETICS IN HDC AND STEM-CELL TRANSPLANTATION PATIENTS
    Ozaydin, S.
    Ozturk, M.
    LEUKEMIA RESEARCH, 2014, 38 : S51 - S51
  • [28] Transfusion strategies in patients undergoing stem-cell transplantation
    Radia, Rohini
    Pamphilon, Derwood
    EXPERT REVIEW OF HEMATOLOGY, 2011, 4 (02) : 213 - 220
  • [29] High-dose chemotherapy with autologous stem-cell support for germ cell tumors: A critical review
    Sobecks, RM
    Vogelzang, NJ
    SEMINARS IN ONCOLOGY, 1999, 26 (01) : 106 - 118
  • [30] Re: High-dose chemotherapy and stem-cell rescue for metastatic germ-cell tumors
    Einhorn, L. H.
    Williams, S. D.
    Chamness, A.
    Brames, M. J.
    Perkins, S. M.
    Abonour, R.
    Gasser, Thomas
    EUROPEAN UROLOGY, 2007, 52 (06) : 1795 - 1796