Synthesis and characterization of some new 2-hydroxy-n-(3-trifluoromethyl-phenyl)-benzamide derivatives

被引：0

作者：

Ienascu, Ioana M. C. ^{[1
]}

Lupea, Alfa X. ^{[1
]}

Popescu, Iuliana M. ^{[2
]}

Tomas, Stefan Th. ^{[3
]}

Zamfir, Alina D. ^{[4
,5
]}

机构：

[1] Polytech Univ, Fac Ind Chem & Environm Engn, Dept Organ Chem, Timisoara 300006, Romania

[2] Banat Agr Sci Univ, Fac Agr, Dept Chem & Biochem, Timisoara 300645, Romania

[3] Polytech Univ, Fac Appl Chem & Mat Sci, Dept Organ Technol & Macromol Cpds, Bucharest 71101, Romania

[4] Natl Inst Res & Dev Electrochem & Condensed Matte, Mass Spectrometry Lab, Timisoara 300224, Romania

[5] Aurel Vlaicu Univ Arad, Arad, Romania

来源：

REVISTA DE CHIMIE | 2008年 / 59卷 / 01期

关键词：

2-hydroxy-N-(3-trifluoromethyl-phenyl)-benzamide derivatives; ethyl esters; hydrazides; hydrazones; salicylanilide-O-substituted;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the reaction between 2-hydroxy-N-(3-trifluoromethyl-phenyl)-benzamide and chloro-acetic acid ethyl ester, [2-(3-trifluoromethyl-phenylcarbamoyl)-phenoxy]-acetic acid ethyl ester was obtained. The ethyl ester was condensed with hydrazine giving 2-hydrazinocarbonylmethoxy-N-(3-trifluoromethyl-phenyl)-benzamide. This hydrazide is considered the key intermediate for the synthesis of new compounds. So, in the reaction between hydrazide and chloro-substituted benzaldehydes hydrazones were obtained. In order to establish their structures, all new synthesized compounds were analyzed by modern physico-chemical methods (FTIR,H-1-NMR, C-13-NMR, MS).

引用

页码：56 / 59

页数：4

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